Alzheimer's disease (AD) is a neurodegenerative disorder characterized by decreased
synaptic transmission and cerebral atrophy with appearance of amyloid plaques and …

The potential to treat neurodegenerative diseases (NDs) of the major bioactive compound of
green tea, epigallocatechin-3-gallate (EGCG), is well documented. Numerous findings now …

With innumerable clinical failures of target-specific drug candidates for multifactorial
diseases, such as Alzheimer's disease (AD), which remains inefficiently treated, the advent …

Alzheimer's disease (AD) is a detrimental neurodegenerative disease that progressively
worsens with time. Clinical options are limited and only provide symptomatic relief to AD …

The complex and multifaceted nature of Alzheimer's disease has brought about a pressing
demand to develop ligands targeting multiple pathways to combat its outrageous …

Alzheimer's disease is becoming a growing problem increasing at a tremendous rate.
Serotonin 5-HT 6 receptors appear to be a particularly attractive target from a therapeutic …

Introduction Alzheimer's disease (AD) constitutes one of the most devastating diseases, with
an extraordinarily high increase expected for the next few years. Despite the numerous …

Based on the multitarget strategy, a series of novel clioquinol− 1-benzyl-1, 2, 3, 6-
tetrahydropyridine hybrids were identified for the potential treatment of Alzheimer's disease …

Alzheimer's disease (AD) is multifactorial, progressive and the most predominant cause of
cognitive impairment and dementia worldwide. The current “one-drug, one-target” approach …

The multifactorial nature of some diseases, particularly neurodegenerative diseases such as
Alzheimer's disease, frequently requires the use of several drugs. These drug cocktails are …