[HTML][HTML] Deep learning in cancer genomics and histopathology

M Unger, JN Kather - Genome Medicine, 2024 - Springer
Histopathology and genomic profiling are cornerstones of precision oncology and are
routinely obtained for patients with cancer. Traditionally, histopathology slides are manually …

From whole-slide image to biomarker prediction: end-to-end weakly supervised deep learning in computational pathology

OSM El Nahhas, M van Treeck, G Wölflein, M Unger… - Nature …, 2024 - nature.com
Hematoxylin-and eosin-stained whole-slide images (WSIs) are the foundation of diagnosis
of cancer. In recent years, development of deep learning-based methods in computational …

[HTML][HTML] Evaluating the efficacy of ChatGPT in navigating the Spanish medical residency entrance examination (MIR): Promising horizons for AI in clinical medicine

F Guillen-Grima, S Guillen-Aguinaga… - Clinics and …, 2023 - mdpi.com
The rapid progress in artificial intelligence, machine learning, and natural language
processing has led to increasingly sophisticated large language models (LLMs) for use in …

Artificial Intelligence in Colorectal Cancer: From Patient Screening over Tailoring Treatment Decisions to Identification of Novel Biomarkers

NG Reitsam, JS Enke, K Vu Trung, B Märkl, JN Kather - Digestion, 2024 - karger.com
Background: Artificial intelligence (AI) is increasingly entering and transforming not only
medical research but also clinical practice. In the last 10 years, new AI methods have …

From whole-slide image to biomarker prediction: a protocol for end-to-end deep learning in computational pathology

OSM El Nahhas, M van Treeck, G Wölflein… - arXiv preprint arXiv …, 2023 - arxiv.org
Hematoxylin-and eosin (H&E) stained whole-slide images (WSIs) are the foundation of
diagnosis of cancer. In recent years, development of deep learning-based methods in …

[HTML][HTML] Artificial Intelligence Models for the Detection of Microsatellite Instability from Whole-Slide Imaging of Colorectal Cancer

G Faa, F Coghe, A Pretta, M Castagnola… - Diagnostics, 2024 - ncbi.nlm.nih.gov
With the advent of whole-slide imaging (WSI), a technology that can digitally scan whole
slides in high resolution, pathology is undergoing a digital revolution. Detecting …

[HTML][HTML] Deep learning for dual detection of microsatellite instability and POLE mutations in colorectal cancer histopathology

M Gustav, NG Reitsam, ZI Carrero, CML Loeffler… - NPJ Precision …, 2024 - nature.com
In the spectrum of colorectal tumors, microsatellite-stable (MSS) tumors with DNA
polymerase ε (POLE) mutations exhibit a hypermutated profile, holding the potential to …

[HTML][HTML] Breaking Barriers: AI's Influence on Pathology and Oncology in Resource-Scarce Medical Systems

A Vigdorovits, MM Köteles, GE Olteanu, O Pop - Cancers, 2023 - mdpi.com
Simple Summary The quality of care available to cancer patients is highly constrained by the
presence of comprehensive pathology services. However, pathology infrastructure is …

Artificial intelligence in liver cancer—new tools for research and patient management

J Calderaro, L Žigutytė, D Truhn, A Jaffe… - Nature Reviews …, 2024 - nature.com
Liver cancer has high incidence and mortality globally. Artificial intelligence (AI) has
advanced rapidly, influencing cancer care. AI systems are already approved for clinical use …

Near-infrared circularly polarized light triggered phototherapy based on hybrid CuInSe2 quantum dot hydrogels

H Gao, Y Liu, W Lian, P Hu, X Shang, M Chen, X Song… - Nano Today, 2024 - Elsevier
For malignant tumor phototherapy, current biomolecules-based materials face challenges
such as limited tissue penetration, insufficient tumor accumulation, and overlook of the …