What is the role of the hippocampus and parahippocampal gyrus in the persistence of tinnitus?
The hippocampus and parahippocampal gyrus have been implicated as part of a tinnitus
network by a number of studies. These structures are usually considered in the context of a …
network by a number of studies. These structures are usually considered in the context of a …
[HTML][HTML] A Systematic Review on the Genetic Contribution to Tinnitus
P Perez-Carpena, JA Lopez-Escamez… - Journal of the …, 2024 - Springer
Purpose To assess the available evidence to support a genetic contribution and define the
role of common and rare variants in tinnitus. Methods After a systematic search and quality …
role of common and rare variants in tinnitus. Methods After a systematic search and quality …
[HTML][HTML] Genetic architecture distinguishes tinnitus from hearing loss
RE Clifford, AX Maihofer, C Chatzinakos… - Nature …, 2024 - nature.com
Tinnitus is a heritable, highly prevalent auditory disorder treated by multiple medical
specialties. Previous GWAS indicated high genetic correlations between tinnitus and …
specialties. Previous GWAS indicated high genetic correlations between tinnitus and …
[HTML][HTML] Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically …
SM Díaz-Rodríguez, MJ Herrero-Turrión… - Frontiers in Molecular …, 2024 - frontiersin.org
Genetic abnormalities affecting glutamate receptors are central to excitatory overload-driven
neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy …
neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy …
[HTML][HTML] Rare deletions or large duplications contribute to genetic variation in patients with severe tinnitus and Meniere disease
A Escalera-Balsera, AM Parra-Perez… - Genes, 2023 - mdpi.com
Meniere disease (MD) is a debilitating disorder of the inner ear defined by sensorineural
hearing loss (SNHL) associated with episodes of vertigo and tinnitus. Severe tinnitus, which …
hearing loss (SNHL) associated with episodes of vertigo and tinnitus. Severe tinnitus, which …
[HTML][HTML] Identifying Health-Related Conditions Associated with Tinnitus in Young Adults
Objective: The present study investigated the epidemic of tinnitus in college-aged young
adults. Our first objective was to identify health conditions associated with tinnitus in young …
adults. Our first objective was to identify health conditions associated with tinnitus in young …
Tinnitus Mechanisms and the Need for an Objective Electrophysiological Tinnitus Test. A Review.
E Fabrizio-Stover, DL Oliver, AL Burghard - Hearing Research, 2024 - Elsevier
Tinnitus, the perception of sound with no external auditory stimulus, is a complex,
multifaceted, and potentially devastating disorder. Despite recent advances in our …
multifaceted, and potentially devastating disorder. Despite recent advances in our …
Treatment outcomes in tinnitus patients are associated with brain functional network: evidence from connectome gradient and gene expression analysis
The neuroimaging mechanisms underlying differences in the outcomes of sound therapy for
tinnitus patients remain unclear. We hypothesize that abnormal hierarchical architecture is …
tinnitus patients remain unclear. We hypothesize that abnormal hierarchical architecture is …
[HTML][HTML] Mice prone to tinnitus after acoustic trauma show increased pre-exposure sensitivity to background noise
N Rybalko, Š Suchánková, Z Bureš… - Frontiers in Behavioral …, 2023 - frontiersin.org
Noise-induced tinnitus is generally associated with hearing impairment caused by traumatic
acoustic overexposure. Previous studies in laboratory animals and human subjects …
acoustic overexposure. Previous studies in laboratory animals and human subjects …
[HTML][HTML] Development, Insults and Predisposing Factors of the Brain's Predictive Coding System to Chronic Perceptual Disorders—A Life-Course Examination
A Yasoda-Mohan, S Vanneste - Brain Sciences, 2024 - mdpi.com
The predictive coding theory is currently widely accepted as the theoretical basis of
perception and chronic perceptual disorders are explained as the maladaptive …
perception and chronic perceptual disorders are explained as the maladaptive …