The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …

Per occasion, alcohol consumption is higher in adolescents than in adults in both humans
and laboratory animals, with changes in the adolescent brain probably contributing to this …

Background Attention-deficit/hyperactivity disorder (ADHD) is among the most common
psychiatric disorders of childhood that often persists into adulthood and old age. Yet ADHD …

Early adolescent substance use dramatically increases the risk of lifelong substance use
disorder (SUD). An adolescent sensitive period evolved to allow the development of risk …

Social cognitive processes are critical in navigating complex social interactions and are
associated with a network of brain areas termed the 'social brain'. Here, we describe the …

Background Adolescence is a critical biological, psychological, and social developmental
stage involving heightened risk for substance use and associated adverse consequences …

Adolescence is the transition from childhood to adulthood that begins around the onset of
puberty and ends with relative independence from the parent. This developmental period is …

Depression is apparently the most common psychiatric disease among the mood disorders
affecting about 10% of the adult population. The etiology and pathogenesis of depression …

El comportamiento epidemiológico de problemas de salud pública como el suicidio, la
depresión, la violencia sexual y el consumo de sustancias, entre otros, tienden al aumento …

Astrocytes play crucial roles in brain homeostasis and are regulatory elements of neuronal
and synaptic physiology. Astrocytic alterations have been found in Major Depressive …