The role of toll-like receptors 2 and 4 in the pathogenesis of chronic obstructive pulmonary disease

K Sidletskaya, T Vitkina… - International journal of …, 2020 - Taylor & Francis
Currently, chronic obstructive pulmonary disease (COPD) is one of the leading causes of
morbidity and mortality worldwide. The determination of immune mechanisms of …

[HTML][HTML] Oral feeding with probiotic Lactobacillus rhamnosus attenuates cigarette smoke-induced COPD in C57Bl/6 mice: Relevance to inflammatory markers in …

JL Carvalho, M Miranda, AK Fialho… - PLoS …, 2020 - journals.plos.org
COPD is a prevalent lung disease with significant impacts on public health. Affected airways
exhibit pulmonary neutrophilia and consequent secretion of pro-inflammatory cytokines and …

[HTML][HTML] Functional variations of the TLR4 gene in association with chronic obstructive pulmonary disease and pulmonary tuberculosis

Z Li, X Mao, Q Liu, H Song, B He, P Shi, Q Zhang… - BMC Pulmonary …, 2019 - Springer
Objective Chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis (PTB)
share a number of common risk factors, including innate immunity-related genetic factors. In …

Role of Toll‐Like Receptor 2 in Regulation of T‐Helper Immune Response in Chronic Obstructive Pulmonary Disease

KA Sidletskaya, TI Vitkina… - Canadian …, 2021 - Wiley Online Library
Objective. According to modern views, the differences in the clinical course of chronic
obstructive pulmonary disease (COPD) are associated with certain types of T‐helper (Th) …

[HTML][HTML] Synonymous mutations in TLR2 and TLR9 genes decrease COPD susceptibility in the Chinese Han population

X Ding, Q Lin, J Zhao, Y Fu, Y Zheng, R Mo, L Zhang… - Pulmonology, 2022 - Elsevier
Introduction Previous studies have found associations between polymorphisms in some
candidate genes and chronic obstructive pulmonary disease (COPD) risk. However, the …

Association of mannose binding lectin with chronic obstructive pulmonary disease susceptibility and its clinical outcomes

A Sharma, SS Kashyap, NC Kajal, B Malhotra… - Molecular Biology …, 2023 - Springer
Background The physiological interactions of MBL suggest its contribution towards the
pathogenesis of COPD. Objective The present case–control study was undertaken to …

[HTML][HTML] Increased HSP70 and TLR2 Gene Expression and Association of HSP70 rs6457452 Single Nucleotide Polymorphism with the Risk of Chronic Obstructive …

I Hlapčić, M Grdić Rajković, A Čeri, S Dabelić… - Diagnostics, 2021 - mdpi.com
Heat shock protein 70 (Hsp70) engages Toll-like receptors (TLR) 2 and 4 when found in the
extracellular compartment and contributes to inflammation in chronic obstructive pulmonary …

[HTML][HTML] Association of toll-like receptors polymorphisms with COPD risk in Chinese population

S Sun, Y Shen, J Feng - Frontiers in Genetics, 2022 - frontiersin.org
Background: Previous studies have reported that the Toll-like receptors (TLRs) are related
with the progress of chronic obstructive pulmonary disease (COPD). We aimed to explore …

Is There an Association Between NOD2 Gene Polymorphisms and Chronic Obstructive Pulmonary Disease Progression?

FM Icduygu, MO Erdogan, SS Ulasli… - … Journal of Human …, 2017 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow
limitation associated with an increased chronic inflammation. Recent studies suggest that …

[PDF][PDF] Increased HSP70 and TLR2 Gene Expression and Association of HSP70 rs6457452 Single Nucleotide Polymorphism with the Risk of Chronic Obstructive …

I Hlapcic, M Grdic Rajkovic, A Ceri… - … oka 70 i adenozin …, 2021 - repozitorij.pharma.unizg.hr
Heat shock protein 70 (Hsp70) engages Toll-like receptors (TLR) 2 and 4 when found in the
extracellular compartment and contributes to inflammation in chronic obstructive pulmonary …