The number of approved biopharmaceuticals, where product quality attributes remain of
major importance, is increasing steadily. Within the available variety of expression hosts, the …

Baculoviruses are arthropod-specific large circular double-stranded DNA viruses
successfully used for the control of multiple insect pests. In addition to their application in …

Monoclonal antibodies (mAbs) are amazingly successful in treating diseases such as
various types of cancers, immune disorders, and infections. Currently, mAbs are considered …

The insect cell-baculovirus expression system technology (BEST) has a prominent role in
producing recombinant proteins to be used as research and diagnostic reagents and …

Selectins are key to mediating interactions involved in cellular adhesion and migration,
underlying processes such as immune responses, metastasis, and transplantation. Selectins …

Glycans have been shown to play a key role in many biological processes, such as signal
transduction, immunogenicity, and disease progression. Among the various glycosylation …

The silkworm-baculovirus expression vector system (silkworm-BEVS), using Bombyx mori
nucleopolyhedrovirus (BmNPV) and silkworm larvae or pupae, has been used as a cost …

N-glycans are involved in various physiological functions and their structures diverge among
different phyla and kingdoms. Insect cells mainly produce high mannose-type and …

Silkworm Bombyx mori is one of the insect hosts for recombinant protein production at
academic and industrial levels. B. mori and other insect cells can produce mammalian …

Glycophobia in structural biology is strongly associated with the unpredictable,
heterogeneous nature of protein glycosylation and the complex, flexible structures of the …