Neoadjuvant hormonal therapy before radical prostatectomy in high-risk prostate cancer

G Devos, W Devlies, G De Meerleer… - Nature Reviews …, 2021 - nature.com
Patients with high-risk prostate cancer treated with curative intent are at an increased risk of
biochemical recurrence, metastatic progression and cancer-related death compared with …

Targeted radionuclide therapy of prostate cancer—from basic research to clinical perspectives

M Czerwińska, A Bilewicz, M Kruszewski… - Molecules, 2020 - mdpi.com
Prostate cancer is the most commonly diagnosed malignancy in men and the second
leading cause of cancer-related deaths in Western civilization. Although localized prostate …

Palmitic acid inhibits prostate cancer cell proliferation and metastasis by suppressing the PI3K/Akt pathway

S Zhu, W Jiao, Y Xu, L Hou, H Li, J Shao, X Zhang… - Life Sciences, 2021 - Elsevier
Aims Prostate cancer is one of the most frequent causes of cancer death in men worldwide,
and novel drugs for prostate cancer therapies are still being developed. Palmitic acid is a …

Progress in delivery of siRNA-based therapeutics employing nano-vehicles for treatment of prostate cancer

M Ashrafizadeh, K Hushmandi, E Rahmani Moghadam… - Bioengineering, 2020 - mdpi.com
Prostate cancer (PCa) accounts for a high number of deaths in males with no available
curative treatments. Patients with PCa are commonly diagnosed in advanced stages due to …

Apalutamide, darolutamide and enzalutamide for nonmetastatic castration-resistant prostate cancer (nmCRPC): a critical review

C Cattrini, O Caffo, U De Giorgi, A Mennitto, A Gennari… - Cancers, 2022 - mdpi.com
Simple Summary Apalutamide, darolutamide and enzalutamide are androgen-receptor
signaling inhibitors proved to be useful in patients with nonmetastatic castration-resistant …

Intermittent versus continuous androgen deprivation therapy for advanced prostate cancer

M Perera, MJ Roberts, L Klotz, CS Higano… - Nature Reviews …, 2020 - nature.com
Androgen deprivation therapy (ADT) is still a mainstay of treatment for advanced prostate
cancer. Continuous ADT causes considerable patient morbidity including sexual …

Management of patients with metastatic castration-sensitive prostate cancer in the real-world setting in the United States

CJ Ryan, X Ke, MH Lafeuille, H Romdhani… - The Journal of …, 2021 - auajournals.org
Purpose: This study provides a contemporary assessment of the treatment patterns, health
care resource utilization (HRU) and costs among metastatic castration-sensitive prostate …

Optimal sequencing and predictive biomarkers in patients with advanced prostate cancer

C Cattrini, R España, A Mennitto, M Bersanelli… - Cancers, 2021 - mdpi.com
Simple Summary Several strategies have demonstrated the ability to improve the survival of
patients with both metastatic and nonmetastatic prostate cancer. The old backbone of …

Prostate cancer and microRNAs: New insights into apoptosis

J Gupta, WK Abdulsahib, AT Jalil, DS Kareem… - … -Research and Practice, 2023 - Elsevier
Prostate cancer (PCa) is known as one of the most prevalent malignancies globally and is
not yet curable owing to its progressive nature. It has been well documented that Genetic …

Angiogenesis and prostate cancer: MicroRNAs comes into view

J Gupta, NA Tayyib, AT Jalil, SH Hlail… - … -Research and Practice, 2023 - Elsevier
Angiogenesis, the formation of new blood vessels, is an important stage in the growth of
cancer. Extracellular matrix, endothelial cells, and soluble substances must be carefully …