Epithelial cells are the first line of mucosal defense. In the intestine, a single layer of
epithelial cells must establish a selectively permeable barrier that supports nutrient …

Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial,
immunological, and genetic factors. Alterations in the gut microbiota have been associated …

The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …

The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …

Backgrounds & Aims Increased permeability is implicated in the pathogenesis of intestinal
disease. In vitro and in vivo studies have linked down-regulation of the scaffolding protein …

The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic,
permeable barrier allowing for selective absorption of nutrients, while restricting access to …

Inflammatory bowel diseases are characterised by inflammation that compromises the
integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has …

Maintaining a healthy gut environment is a prerequisite for sustainable animal production.
The gut plays a key role in the digestion and absorption of nutrients and constitutes an initial …

Polymorphonuclear leukocytes or neutrophils play a critical role in the maintenance of
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …

The intestinal epithelium is a single-cell layer that constitutes the largest and most important
barrier against the external environment. It acts as a selectively permeable barrier …