Tight junction proteins occludin and ZO‐1 as regulators of epithelial proliferation and survival
Epithelial cells are the first line of mucosal defense. In the intestine, a single layer of
epithelial cells must establish a selectively permeable barrier that supports nutrient …
epithelial cells must establish a selectively permeable barrier that supports nutrient …
Inflammatory bowel diseases (IBD) and the microbiome—searching the crime scene for clues
M Lee, EB Chang - Gastroenterology, 2021 - Elsevier
Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial,
immunological, and genetic factors. Alterations in the gut microbiota have been associated …
immunological, and genetic factors. Alterations in the gut microbiota have been associated …
[HTML][HTML] Inflammatory and microbiota-related regulation of the intestinal epithelial barrier
G Barbara, MR Barbaro, D Fuschi, M Palombo… - Frontiers in …, 2021 - frontiersin.org
The intestinal epithelial barrier (IEB) is one of the largest interfaces between the
environment and the internal milieu of the body. It is essential to limit the passage of harmful …
environment and the internal milieu of the body. It is essential to limit the passage of harmful …
[HTML][HTML] Implication of intestinal barrier dysfunction in gut dysbiosis and diseases
The intestinal mucosal barrier, also referred to as intestinal barrier, is widely recognized as a
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …
critical player in gut homeostasis maintenance as it ensures the complex crosstalk between …
The tight junction protein ZO-1 is dispensable for barrier function but critical for effective mucosal repair
Backgrounds & Aims Increased permeability is implicated in the pathogenesis of intestinal
disease. In vitro and in vivo studies have linked down-regulation of the scaffolding protein …
disease. In vitro and in vivo studies have linked down-regulation of the scaffolding protein …
Inflammation and the intestinal barrier: leukocyte–epithelial cell interactions, cell junction remodeling, and mucosal repair
The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic,
permeable barrier allowing for selective absorption of nutrients, while restricting access to …
permeable barrier allowing for selective absorption of nutrients, while restricting access to …
[HTML][HTML] Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer
J Landy, E Ronde, N English, SK Clark… - World journal of …, 2016 - ncbi.nlm.nih.gov
Inflammatory bowel diseases are characterised by inflammation that compromises the
integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has …
integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has …
[HTML][HTML] Enteric pathogens and their toxin-induced disruption of the intestinal barrier through alteration of tight junctions in chickens
WA Awad, C Hess, M Hess - Toxins, 2017 - mdpi.com
Maintaining a healthy gut environment is a prerequisite for sustainable animal production.
The gut plays a key role in the digestion and absorption of nutrients and constitutes an initial …
The gut plays a key role in the digestion and absorption of nutrients and constitutes an initial …
[HTML][HTML] The role of neutrophils during intestinal inflammation
BM Fournier, CA Parkos - Mucosal immunology, 2012 - Elsevier
Polymorphonuclear leukocytes or neutrophils play a critical role in the maintenance of
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …
Intestinal barrier function: molecular regulation and disease pathogenesis
KR Groschwitz, SP Hogan - Journal of allergy and clinical immunology, 2009 - Elsevier
The intestinal epithelium is a single-cell layer that constitutes the largest and most important
barrier against the external environment. It acts as a selectively permeable barrier …
barrier against the external environment. It acts as a selectively permeable barrier …