Off-label use of medication may be presented in these guidelines if a sufficient level of
evidence shows that it can be considered medically appropriate to a given condition and if …

Pulmonary hypertension, defined as an elevation in blood pressure in the pulmonary
arteries, is associated with an increased risk of death. The prevalence of pulmonary …

Background Moderate intraoperative hypothermia promotes myocardial injury, surgical site
infections, and blood loss. Whether aggressive warming to a truly normothermic temperature …

Aims Perioperative myocardial infarction/injury (PMI) following non-cardiac surgery is a
frequent cardiac complication. Better understanding of the underlying aetiologies and …

In accordance with all the most recent international guidelines, the variation of circulating
levels of cardiac troponins I and T, measured with high-sensitivity methods (hs-cTnI and hs …

Myocardial injury is now an acknowledged complication in patients undergoing noncardiac
surgery. Heterogeneity in the definitions of myocardial injury contributes to difficulty in …

Abstract Background and Aims Haemodynamic instability is associated with peri-operative
myocardial injury, particularly in patients receiving renin–angiotensin system (RAS) …

Myocardial injury after non-cardiac surgery (MINS) is strongly associated with postoperative
outcomes. We developed a prediction model for MINS and have provided it online. Between …

Troponin released from irreversibly injured myocytes is the gold standard biomarker for the
rapid identification of an acute coronary syndrome. In acute myocardial infarction, necrotic …

The impact of circadian rhythms on cardiovascular function and disease development is well
established, with numerous studies in genetically modified animals emphasizing the …