Regulated expression of the small nuclear ribonucleoprotein particle protein SmN in embryonic stem cell differentiation
NG Sharpe, DG Williams… - Molecular and cellular …, 1990 - Taylor & Francis
The SmN protein is a component of small nuclear ribonucleoprotein particles and is closely
related to the ubiquitous SmB and B'splicing proteins. It is expressed in a limited range of …
related to the ubiquitous SmB and B'splicing proteins. It is expressed in a limited range of …
Validation of an in vitro RNA processing system for CT/CGRP precursor mRNA
GJ Cote, N Nguyen, CJM Lips, SM Berget… - Nucleic acids …, 1991 - academic.oup.com
The pre-mRNA encodlng calcitonin (CT) and calcitonin gene-related peptide (CGRP) is
differentially processed in a tissue-specific fashion to include or exclude the calcitonin …
differentially processed in a tissue-specific fashion to include or exclude the calcitonin …
Isolation of cDNA clones encoding small nuclear ribonucleoparticle-associated proteins with different tissue specificities.
S Li, ES Klein, AF Russo… - Proceedings of the …, 1989 - National Acad Sciences
Alternative RNA processing, such as brain-and heart-specific generation of calcitonin gene-
related peptide (CGRP) transcripts from the calcitonin/CGRP gene, is thought to be …
related peptide (CGRP) transcripts from the calcitonin/CGRP gene, is thought to be …
Selective pituitary resistance to thyroid hormone produced by expression of a mutant thyroid hormone receptor β gene in the pituitary gland of transgenic mice
Y Hayashi, J Xie, RE Weiss, J Pohlenz… - … and biophysical research …, 1998 - Elsevier
Resistance to thyroid hormone (RTH) has been subdivided into generalized resistance
(GRTH) and pituitary resistance (PRTH) based on the clinical impression of absence or …
(GRTH) and pituitary resistance (PRTH) based on the clinical impression of absence or …
Thyroid hormone receptor β1 expression in developing mouse limbs and face
T Nagasawa, S Suzuki, T Takeda, LJ DeGroot - Endocrinology, 1997 - academic.oup.com
Thyroid hormone, acting through thyroid hormone receptors (TRs), plays an important role in
amphibian metamorphosis and vertebrate development. To identify where and when TRβ1 …
amphibian metamorphosis and vertebrate development. To identify where and when TRβ1 …
Model for tissue specific Calcitonin/CGRP-I RNA processing from in vitro experiments
RAL Bovenberg, GJ Adema, HS Jansz… - Nucleic acids …, 1988 - academic.oup.com
Abstract The Calcitonin/CGRP-I (CALC-I) gene is known to be expressed in a tissue specific
fashion resulting in the production of Calcitonin mRNA in thyroid C-cells and CGRP-I mRNA …
fashion resulting in the production of Calcitonin mRNA in thyroid C-cells and CGRP-I mRNA …
A nonimmunoglobulin transgene and the endogenous immunoglobulin μ gene are coordinately regulated by alternative RNA processing during B-cell maturation
RL Seipelt, BT Spear, EC Snow… - Molecular and cellular …, 1998 - Am Soc Microbiol
The immunoglobulin (Ig) genes have been extensively studied as model systems for
developmentally regulated alternative RNA processing. Transcripts from these genes are …
developmentally regulated alternative RNA processing. Transcripts from these genes are …
Calcitonin-specific transcription and splicing targets gene-directed enzyme prodrug therapy to medullary thyroid carcinoma cells
M Messina, DMT Yu, GW Both, PL Molloy… - The Journal of …, 2003 - academic.oup.com
Recurrent and metastatic medullary thyroid carcinoma (MTC) remains difficult to treat due to
its limited responsiveness to chemotherapy, radiotherapy, and imaging. To investigate an …
its limited responsiveness to chemotherapy, radiotherapy, and imaging. To investigate an …
Expression of the tissue specific splicing protein SmN in neuronal cell lines and in regions of the brain with different splicing capacities
DA Horn, A Suburo, G Terenghi, LD Hudson… - Molecular brain …, 1992 - Elsevier
The SmN protein is closely related to the ubiquitously expressed SmB and B′ RNA splicing
proteins but is expressed in only a limited range of tissues and cell types. The expression of …
proteins but is expressed in only a limited range of tissues and cell types. The expression of …
Expression of the SmB′ splicing protein in rodent cells capable of following an alternative RNA splicing pathway
NG Sharpe, DG Williams, P Norton… - FEBS letters, 1989 - Wiley Online Library
The expression of the SmB and SmB′ spliceosome proteins in a variety of cell types and
tissues has been investigated. Although SmB is found in all cells studied, the SmB′ protein …
tissues has been investigated. Although SmB is found in all cells studied, the SmB′ protein …