Towards controlled drug delivery in brain tumors with microbubble-enhanced focused ultrasound
Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …
Ultrasound contrast imaging: Fundamentals and emerging technology
H Yusefi, B Helfield - Frontiers in Physics, 2022 - frontiersin.org
The development of microbubble contrast agents has broadened the scope of medical
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …
Probing the pressure dependence of sound speed and attenuation in bubbly media: Experimental observations, a theoretical model and numerical calculations
The problem of attenuation and sound speed of bubbly media has remained partially
unsolved. Comprehensive data regarding pressure-dependent changes of the attenuation …
unsolved. Comprehensive data regarding pressure-dependent changes of the attenuation …
Nonlinear dynamics of acoustic bubbles excited by their pressure-dependent subharmonic resonance frequency: influence of the pressure amplitude, frequency …
Nonlinear behavior of bubbles, and most importantly 1 2 1 2-order subharmonics (SH), are
used to increase the contrast-to-tissue ratio (CTR) in diagnostic ultrasound (US) and to …
used to increase the contrast-to-tissue ratio (CTR) in diagnostic ultrasound (US) and to …
Toward precisely controllable acoustic response of shell-stabilized nanobubbles: High yield and narrow dispersity
A Jafari Sojahrood, AC de Leon, R Lee, M Cooley… - ACS …, 2021 - ACS Publications
Understanding the pressure dependence of the nonlinear behavior of ultrasonically excited
phospholipid-stabilized nanobubbles (NBs) is important for optimizing ultrasound exposure …
phospholipid-stabilized nanobubbles (NBs) is important for optimizing ultrasound exposure …
A review of phospholipid encapsulated ultrasound contrast agent microbubble physics
B Helfield - Ultrasound in medicine & biology, 2019 - Elsevier
Ultrasound contrast agent microbubbles have expanded the utility of biomedical ultrasound
from anatomic imaging to the assessment of microvascular blood flow characteristics and …
from anatomic imaging to the assessment of microvascular blood flow characteristics and …
Targeted microbubbles for drug, gene, and cell delivery in therapy and immunotherapy
JA Navarro-Becerra, MA Borden - Pharmaceutics, 2023 - mdpi.com
Microbubbles are 1–10 μm diameter gas-filled acoustically-active particles, typically
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …
stabilized by a phospholipid monolayer shell. Microbubbles can be engineered through …
[HTML][HTML] The influence of inter-bubble spacing on the resonance response of ultrasound contrast agent microbubbles
H Yusefi, B Helfield - Ultrasonics Sonochemistry, 2022 - Elsevier
Ultrasound-driven microbubbles, typically between 1 and 8 µm in diameter, are resonant
scatterers that are employed as diagnostic contrast agents and emerging as potentiators of …
scatterers that are employed as diagnostic contrast agents and emerging as potentiators of …
[HTML][HTML] Nonlinear dynamics and bifurcation structure of ultrasonically excited lipid coated microbubbles
In many applications, microbubbles (MBs) are encapsulated by a lipid coating to increase
their stability. However, the complex behavior of the lipid coating including buckling and …
their stability. However, the complex behavior of the lipid coating including buckling and …
[HTML][HTML] Sonobactericide: an emerging treatment strategy for bacterial infections
KR Lattwein, H Shekhar, JJP Kouijzer… - Ultrasound in medicine …, 2020 - Elsevier
Ultrasound has been developed as both a diagnostic tool and a potent promoter of
beneficial bio-effects for the treatment of chronic bacterial infections. Bacterial infections …
beneficial bio-effects for the treatment of chronic bacterial infections. Bacterial infections …