Pancreatic ductal adenocarcinoma (PDAC) is considered one of the deadliest malignancies,
with dismal survival rates and extremely prevalent chemoresistance. Gemcitabine is one of …

Cancer-related death is a significant health and economic burden worldwide, and some
conventional chemotherapy is associated with limited effectiveness in completely curing …

Simple Summary Metronomic chemotherapy, a continuous administration of a lowered dose
of drugs without long breaks, is currently considered an alternative approach for the …

Simple Summary In this retrospective analysis of 72 advanced ovarian cancer patients, we
have evaluated the safety and activity of orally-administered metronomic chemotherapy …

For decades, mathematical models have influenced how we schedule chemotherapeutics.
More recently, mathematical models have leveraged lessons from ecology, evolution, and …

Background: Breast cancer, with 2.3 million new cases and 0.7 million deaths every year,
represents a great medical challenge worldwide. These numbers confirm that approx. 30 …

Metronomic chemotherapy (mCHT), defined as continuous administration of low-dose
chemotherapeutic agents with no or short regular treatment-free intervals, was first …

Simple Summary The present review summarizes and interprets uniform therapy schemes
for rescuing relapsed or refractory (r/r) neoplasias of quite different histologic origins …

Despite the significant expansion of the therapeutic armamentarium associated with the
introduction of novel endocrine therapies, cytotoxic agents, radiopharmaceuticals, and …

Simple Summary A prognostic assessment is crucial for making cancer treatment decisions.
However, the frequent presence of comorbidities makes this assessment particularly …