[HTML][HTML] DCRM 2.0: Multispecialty practice recommendations for the management of diabetes, cardiorenal, and metabolic diseases

Y Handelsman, JE Anderson, GL Bakris… - Metabolism, 2024 - Elsevier
The spectrum of cardiorenal and metabolic diseases comprises many disorders, including
obesity, type 2 diabetes (T2D), chronic kidney disease (CKD), atherosclerotic cardiovascular …

[HTML][HTML] The importance of LDL-C lowering in atherosclerotic cardiovascular disease prevention: Lower for longer is better

O Mhaimeed, ZA Burney, SL Schott, P Kohli… - American Journal of …, 2024 - Elsevier
Cumulative exposure to low-density lipoprotein cholesterol (LDL-C) is a key driver of
atherosclerotic cardiovascular disease (ASCVD) risk. An armamentarium of therapies to …

Exome sequence analysis identifies rare coding variants associated with a machine learning-based marker for coronary artery disease

BO Petrazzini, IS Forrest, G Rocheleau, HMT Vy… - Nature Genetics, 2024 - nature.com
Coronary artery disease (CAD) exists on a spectrum of disease represented by a
combination of risk factors and pathogenic processes. An in silico score for CAD built using …

Cytokines, C-Reactive Protein, and Risk of Incident Hypertension in the REGARDS Study

TB Plante, SP Juraschek, G Howard, VJ Howard… - …, 2024 - Am Heart Assoc
BACKGROUND: Hypertension is a highly prevalent cardiovascular disease risk factor that
may be related to inflammation. Whether adverse levels of specific inflammatory cytokines …

Lipid Oxidation Products and the Risk of Cardiovascular Diseases: Role of Lipoprotein Transport

M Ahotupa - Antioxidants, 2024 - mdpi.com
Cholesterol has for decades ruled the history of atherosclerotic cardiovascular diseases
(CVDs), and the present view of the etiology of the disease is based on the transport of …

More than just a number: perspectives from black male participants on community-based interventions and clinical trials to address cardiovascular health disparities

FE Metlock, S Addison, A McKoy, Y Yang… - International Journal of …, 2024 - mdpi.com
Background: Black Americans remain significantly underrepresented and understudied in
research. Community-based interventions have been increasingly recognized as an …

Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke

C Wei, Z Xiao, Y Zhang, Z Luo, D Liu, L Hu… - Cell Death & …, 2024 - nature.com
Neuronal ferroptosis plays a key role in neurologic deficits post intracerebral hemorrhage
(ICH). However, the endogenous regulation of rescuing ferroptotic neurons is largely …

Arrhythmias and ion channelopathies causing sudden cardiac death in Hispanic/Latino and Indigenous populations

S Zaveri, M Chahine, M Boutjdir - Journal of Cardiovascular …, 2024 - Wiley Online Library
The limited literature and increasing interest in studies on cardiac electrophysiology,
explicitly focusing on cardiac ion channelopathies and sudden cardiac death in diverse …

Circadian Mechanisms in Cardiovascular and Cerebrovascular Disease

EH Lo, FM Faraci - Circulation Research, 2024 - Am Heart Assoc
All living organisms on Earth demonstrate rhythms in biological function, which are
approximately tied to the 24-hour cycle of a single day and night. The term diurnal is …

[HTML][HTML] Feasibility and Cardiometabolic Effects of Time-Restricted Eating in Patients with Metabolic Syndrome

I Świątkiewicz, J Nuszkiewicz, J Wróblewska… - Nutrients, 2024 - mdpi.com
Metabolic syndrome (MetS) and a prolonged daily eating window (EW) are associated with
circadian rhythm disruption and increased cardiometabolic risk. Misalignment between …