Kynurenines and PACAP in migraine: medicinal chemistry and pathogenetic aspects

J Tajti, D Szok, G Nagy-Grocz, B Tuka… - Current medicinal …, 2017 - ingentaconnect.com
Background: Migraine is a highly disabling neurovascular primary headache disorder, with
its exact pathomechanism being still unrevealed. The current leading hypotheses are based …

Use of anti-pacap antibodies and antigen binding fragments thereof for treatment, prevention, or inhibition of photophobia

A Kuburas, EW Ojala, FAN Pei, JTL Smith… - US Patent …, 2020 - Google Patents
This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP
receptor antibodies, and antigen binding fragments thereof, for potential use in treating or …

Anti-CGRP compositions and use thereof

BR Kovacevich, LF Garcia-Martinez… - US Patent …, 2018 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
47175055&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Use of anti-pacap antibodies and antigen binding fragments thereof for treatment, prevention, or inhibition of photophobia

A Kuburas, B Mason, LP Sowers, AF Russo… - US Patent App. 15 …, 2016 - Google Patents
This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP
receptor antibodies, and antigen binding fragments thereof, for potential use in treating or …

偏头痛患者降钙素基因相关肽与局部脑血流量变化的相关研究

王淑丽, 牛争平, 周芸, 张亚民, 李险峰 - 中华神经医学杂志, 2015 - cqvip.com
目的研究偏头痛患者发作期降钙素相关基因肽(CGRP) 和局部脑血流的变化及二者的相关性.
方法收集自2010 年5 月至2012 年5 月山西医科大学第一医院神经内科门诊经临床确诊的38 …

Methods of determining whether anti-PACAP antibodies inhibit PACAP-associated photophobia or light aversion

A Kuburas, B Mason, LP Sowers, AF Russo… - US Patent …, 2021 - Google Patents
This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP
receptor antibodies, and antigen binding fragments thereof, for potential use in treating or …

Calcitonin gene-related peptide as a biomarker in migraine

AI Alemam, WM Alsheikh, IA Alahmar - Journal of Neurology Research, 2018 - neurores.org
Background: Migraine is a prevalent disease with much economic burden and relatively
inadequate available treatment. Calcitonin gene-related peptide (CGRP) is the most …

Comparison of the effectiveness of mindfulnessbased stress reduction group therapy with acceptance and commitment therapy on severity of pain and health-related …

T Haji Seyed Javadi, N Aghareb Parast… - International Clinical …, 2019 - archive.pcbmb.org
Objective: Considering the prevalence of migraine and its detrimental effects on functioning,
physical health, and quality of life as well as its psychosocial and social risks, the purpose of …

Anti-CGRP compositions and use thereof

BR Kovacevich, LF Garcia-Martinez… - US Patent …, 2019 - Google Patents
2020-05-08 First worldwide family litigation filed litigation Critical https://patents. darts-ip.
com/? family= 47175055&utm_source= google_patent&utm_medium …

Anti-CGRP compositions and use thereof

BR Kovacevich, LF Garcia-Martinez… - US Patent …, 2019 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
47175055&utm_source= google_patent&utm_medium= platform_link&utm_campaign …