Endothelial dysfunction and chronic inflammation: the cornerstones of vascular alterations in age-related diseases
G Pacinella, AM Ciaccio, A Tuttolomondo - International Journal of …, 2022 - mdpi.com
Vascular diseases of the elderly are a topic of enormous interest in clinical practice, as they
have great epidemiological significance and lead to ever-increasing healthcare …
have great epidemiological significance and lead to ever-increasing healthcare …
Aging of the arterial system
R Castelli, A Gidaro, G Casu, P Merella… - International Journal of …, 2023 - mdpi.com
Aging of the vascular system is associated with deep changes of the structural proprieties of
the arterial wall. Arterial hypertension, diabetes mellitus, and chronic kidney disease are the …
the arterial wall. Arterial hypertension, diabetes mellitus, and chronic kidney disease are the …
Arterial dissections: Common features and new perspectives
Arterial dissections, which involve an abrupt tear in the wall of a major artery resulting in the
intramural accumulation of blood, are a family of catastrophic disorders causing major …
intramural accumulation of blood, are a family of catastrophic disorders causing major …
Changes in arterial stiffness in response to various types of exercise modalities: a narrative review on physiological and endothelial senescence perspectives
S Kresnajati, YY Lin, T Mündel, JR Bernard, HF Lin… - Cells, 2022 - mdpi.com
Arterial stiffness is a reliable independent predictor of cardiovascular events. Exercise
training might enhance arterial compliance through improved metabolic health status …
training might enhance arterial compliance through improved metabolic health status …
Cerebral small vessel disease: a review of the pathophysiological mechanisms
Y Hannawi - Translational Stroke Research, 2023 - Springer
Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …
Environmental and genetic predictors of human cardiovascular ageing
Cardiovascular ageing is a process that begins early in life and leads to a progressive
change in structure and decline in function due to accumulated damage across diverse cell …
change in structure and decline in function due to accumulated damage across diverse cell …
Liquid-liquid phase separation of DDR1 counteracts the Hippo pathway to orchestrate arterial stiffening
J Liu, J Wang, Y Liu, SA Xie, J Zhang, C Zhao… - Circulation …, 2023 - Am Heart Assoc
Background: The Hippo-YAP (yes-associated protein) signaling pathway is modulated in
response to various environmental cues. Activation of YAP in vascular smooth muscle cells …
response to various environmental cues. Activation of YAP in vascular smooth muscle cells …
[HTML][HTML] Sex differences in diagnostic modalities of atherosclerosis in the macrocirculation
PLM Kerkhof, F Tona - Atherosclerosis, 2023 - Elsevier
Asymptomatic atherosclerosis begins early in life and may progress in a sex-specific manner
to become the major cause of cardiovascular morbidity and death. As diagnostic tools to …
to become the major cause of cardiovascular morbidity and death. As diagnostic tools to …
Sex differences in biological systems and the conundrum of menopause: Potential commonalities in post-menopausal disease mechanisms
DA Hart - International Journal of Molecular Sciences, 2022 - mdpi.com
Sex-specific differences in biology and physiology likely start at the time of conception and
progress and mature during the pre-puberty time frame and then during the transitions …
progress and mature during the pre-puberty time frame and then during the transitions …
The extracellular matrix mechanics in the vasculature
D Wang, T Brady, L Santhanam… - Nature Cardiovascular …, 2023 - nature.com
Mechanical stimuli from the extracellular matrix (ECM) modulate vascular differentiation,
morphogenesis and dysfunction of the vasculature. With innovation in measurements, we …
morphogenesis and dysfunction of the vasculature. With innovation in measurements, we …