Many active pharmaceutical ingredients show low oral bioavailability due to factors such as
poor solubility and physical and chemical instability. The formation of inclusion complexes …

Chiral separation, the process of isolating enantiomers from a racemic mixture, holds
paramount importance in diverse scientific disciplines. Using chiral separation methods like …

Ertapenem (ERT) and meropenem (MRP) are widely used carbapenem antibiotics. Their
synergistic combined double regimen effect has been reported against resistant bacteria …

High-pressure liquid chromatography (HPLC) is a technique of paramount importance in the
analysis of pharmaceuticals because of its ability to separate moderately polar to less polar …

For decades now, the separation of chiral enantiomers of drugs has been gaining the
interest and attention of researchers. In 1991, the first guidelines for development of chiral …

Abstract One-factor-at-a-time experimentation was used for a long time as gold-standard
optimization for liquid chromatographic (LC) method development. This approach has two …

Imidocarb dipropionate (IMD) is broadly utilized in veterinary medicine as an antimicrobial to
cure many illnesses, particularly anaplasmosis in livestock. Consequently, the rapid …

Chiral resolution is a technique of choice, making it possible to obtain asymmetric and
enantiomerically pure compounds from a racemic mixture. This study investigated the …

A series of new and novel Chalcone derivatives designated as BA1 to BA8, was synthesized
and investigated in order to explore their potential as pharmaceutical agents. Benzene-di …

An efficient method for the continuous separation of Voriconazole enantiomers was
developed using sulfobutyl ether‐β‐cyclodextrin (SBE‐β‐CD) as a chiral selector in high …