Abstract Aims: Heme oxygenase-1 (HMOX1) is a cytoprotective enzyme degrading heme to
biliverdin, iron ions, and carbon monoxide, whose expression is induced in response to …

Endothelial progenitor cells (EPCs) are responsible for neovascularization of ischaemic
tissue and may participate in re-endothelization of an injured arterial wall. There is evidence …

Heme oxygenase-1 (HO-1), a cytoprotective, pro-angiogenic and anti-inflammatory enzyme,
is strongly induced in injured tissues. Our aim was to clarify its role in cutaneous wound …

Platelet-derived growth factor-BB (PDGF-BB) is a well-characterized growth factor displaying
potent biological effects on angiogenesis. Recent studies reveal that overexpression of …

Carbon monoxide (CO) is generated by heme oxygenase-1 (HO-1) and displays important
signaling, anti-apoptotic and anti-inflammatory activities, indicating that pharmacological …

Objective—Heme oxygenase-1 (HO-1) is an antioxidative, antiinflammatory, and
cytoprotective enzyme that is induced in response to cellular stress. The HO-1 promoter …

Abstract Development of human tumors is driven by accumulation of alterations in tumor
suppressor genes and oncogenes in cells. The POU1F1 transcription factor (also known Pit …

Most of diabetic cardiovascular complications are attributed to endothelial dysfunction and
impaired angiogenesis. Endoplasmic Reticulum (ER) and oxidative stresses were shown to …

Heme oxygenase-1 (HO-1) metabolizes heme to generate carbon monoxide (CO),
biliverdin, and iron. Biliverdin is subsequently metabolized to bilirubin by biliverdin …

Rapid and functional enthesis regeneration after rotator cuff tear (RCT) remains a challenge
in clinic. Current tissue-engineering strategies for solving this challenge are focused on …