Wound healing: from passive to smart dressings

M Farahani, A Shafiee - Advanced Healthcare Materials, 2021 - Wiley Online Library
The universal increase in the number of patients with nonhealing skin wounds imposes a
huge social and economic burden on the patients and healthcare systems. Although, the …

Integrating plant molecular farming and materials research for next-generation vaccines

YH Chung, D Church, EC Koellhoffer, E Osota… - Nature Reviews …, 2022 - nature.com
Biologics—medications derived from a biological source—are increasingly used as
pharmaceuticals, for example, as vaccines. Biologics are usually produced in bacterial …

[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

A review of 3D-printing of microneedles

M Olowe, SK Parupelli, S Desai - Pharmaceutics, 2022 - mdpi.com
Microneedles are micron-sized devices that are used for the transdermal administration of a
wide range of active pharmaceutics substances with minimally invasive pain. In the past …

Recent advances in micro-and nano-scale carrier systems for controlled delivery of vaccines

EY Wang, M Sarmadi, B Ying, A Jaklenec, R Langer - Biomaterials, 2023 - Elsevier
Vaccines provide substantial safety against infectious diseases, saving millions of lives each
year. The recent COVID-19 pandemic highlighted the importance of vaccination in providing …

Rapid induction of long-lasting systemic and mucosal immunity via Thermostable Microneedle-Mediated Chitosan Oligosaccharide-Encapsulated DNA Nanoparticles

M Li, L Yang, C Wang, M Cui, Z Wen, Z Liao, Z Han… - Acs Nano, 2023 - ACS Publications
Most existing vaccines, delivered by intramuscular injection (IM), are typically associated
with stringent storage requirements under cold-chain distribution and professional …

Keratinocyte membrane-mediated nanodelivery system with dissolving microneedles for targeted therapy of skin diseases

Q Jing, H Ruan, J Li, Z Wang, L Pei, H Hu, Z He, T Wu… - Biomaterials, 2021 - Elsevier
There is a lack of actively targeting drug delivery carriers for the topical treatment of
epidermal diseases, which results in drug waste and an increased incidence of toxic side …

Microneedles for efficient and precise drug delivery in cancer therapy

K Ganeson, AH Alias, V Murugaiyah, AAA Amirul… - Pharmaceutics, 2023 - mdpi.com
Cancer is the leading cause of death, acting as a global burden, severely impacting the
patients' quality of life and affecting the world economy despite the expansion of cumulative …

Application of nano-delivery systems in lymph nodes for tumor immunotherapy

Y Xia, S Fu, Q Ma, Y Liu, N Zhang - Nano-micro letters, 2023 - Springer
Immunotherapy has become a promising research “hotspot” in cancer treatment.“Soldier”
immune cells are not uniform throughout the body; they accumulate mostly in the immune …

Advances in nanomedicines for lymphatic imaging and therapy

P He, H Tang, Y Zheng, Y Xiong, H Cheng, J Li… - Journal of …, 2023 - Springer
Lymph nodes play a pivotal role in tumor progression as key components of the lymphatic
system. However, the unique physiological structure of lymph nodes has traditionally …