Macrophages play an important role in a wide variety of physiologic and pathologic
processes. Plasticity and functional polarization are hallmarks of macrophages …

Macrophages represent heterogeneous cell population with important roles in defence
mechanisms and in homoeostasis. Tissue macrophages from diverse anatomical locations …

Tumor-associated macrophages (TAMs) are important immunocytes associated with cancer
metastasis. However, whether TAMs play a dominant role in mediating CXCL12/CXCR4 …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Exosomes are emerging as important elements that participate in intercellular
communication and tumor microenvironment modulation, but the exact mechanisms by …

Inflammation is a hallmark of virtually all liver diseases, such as liver cancer, fibrosis,
nonalcoholic steatohepatitis, alcoholic liver disease, and cholangiopathies. Liver …

Monocytes and macrophages provide defence against pathogens and danger signals.
These cells respond to stimulation in a fast and stimulus-specific manner by utilizing …

Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

Ovarian cancer is the most lethal gynecological malignancy worldwide. Most patients are
diagnosed at late stages because of atypical symptoms and the lack of effective early …

Leishmaniasis is a vector-borne neglected tropical disease that affects more than 700,000
people annually. Leishmania parasites cause the disease, and different species trigger a …