Tetraspanins are a family of proteins with four transmembrane domains that play a role in
many aspects of cell biology and physiology; they are also used by several pathogens for …

Tetraspanins are molecular scaffolds that distribute proteins into highly organized
microdomains consisting of adhesion, signaling, and adaptor proteins. Many reports have …

Exosomes are 40–100-nm-diameter nanovesicles of endocytic origin that are released from
diverse cell types. To better understand the biological role of exosomes and to avoid …

Tumours progress through a cascade of events that enable the formation of metastases.
Some of the components that are required for this fatal process are well established …

The serine/threonine kinase Akt is a master regulator of many diverse cellular functions,
including survival, growth, metabolism, migration, and differentiation. Receptor tyrosine …

The αvβ3 integrin has been shown to promote aggressive phenotypes in many types of
cancers, including prostate cancer. We show that GFP-labeled αvβ3 derived from cancer …

Antibody targeting of cancer is showing clinical and commercial success after much intense
research and development over the last 30 years. They still have the potential to delivery …

The mechanisms driving the development of extracapillary lesions in focal segmental
glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN) remain poorly …

In the present minireview, we intend to provide a brief history of the field of CD9 involvement
in oncogenesis and in the metastatic process of cancer, considering its potential value as a …

Trop-2 is a transmembrane signal transducer that is overexpressed in most human cancers,
and drives malignant progression. To gain knowledge on the higher-order molecular …