[HTML][HTML] Simultaneous multi-site editing of individual genomes using retron arrays

A González-Delgado, SC Lopez, M Rojas-Montero… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Our understanding of genomics is limited by the scale of our genomic technologies. While
libraries of genomic manipulations scaffolded on CRISPR gRNAs have been transformative …

In situ targeted mutagenesis of gut bacteria

AK Brödel, L Charpenay, M Galtier, FJ Fuche… - bioRxiv, 2022 - biorxiv.org
Microbiome research is revealing a growing number of bacterial genes that impact our
health. While CRISPR-derived tools have shown great success in editing disease-driving …

Multiplex CRISPR-Cas Genome Editing: Next-Generation Microbial Strain Engineering

SR Lim, SJ Lee - Journal of agricultural and food chemistry, 2024 - ACS Publications
Genome editing is a crucial technology for obtaining desired phenotypes in a variety of
species, ranging from microbes to plants, animals, and humans. With the advent of CRISPR …

Enhanced chaotrope tolerance and (S)‐2‐hydroxypropiophenone production by recombinant Pseudomonas putida engineered with Pprl from Deinococcus …

R Kordesedehi, A Shahpiri, MA Asadollahi… - Microbial …, 2024 - Wiley Online Library
Pseudomonas putida is a soil bacterium with multiple uses in fermentation and
biotransformation processes. P. putida ATCC 12633 can biotransform benzaldehyde and …

[HTML][HTML] REDOX physical-chemical method boosted phospholytic bacteria technology for enhanced phosphorus solubilization

Y Jiang, T Cui, L Cao, J Huang, Y Tu… - … in Bioengineering and …, 2023 - frontiersin.org
Phosphate-solubilizing bacteria are the bacteria that secrete organic acids and
phosphatases to convert the insoluble phosphorus fixed in soil into soluble phosphorus …

In vivo fluorine biocatalysis: Six enzymes in search of a cell factory

PI Nikel, DH Welner, A Cros, DC Volke - Chem Catalysis, 2022 - cell.com
In this Activity article, Pablo I. Nikel, Ditte H. Welner (senior researchers and group leaders),
Antonin Cros (PhD student), Daniel Volke (tenure-track researcher) at the Novo Nordisk …

Advances and applications of gene editing and transcriptional regulation in electroactive microorganisms

C Yaru, CAO Yingxiu, S Hao - Synthetic Biology Journal, 2023 - synbioj.cip.com.cn
Electroactive microorganisms (EAMs) engage in bidirectional electron exchange with
extracellular electron acceptors/donors through the extracellular electron transfer (EET) …

[HTML][HTML] The development of an ingestible biosensor for the characterization of gut metabolites related to major depressive disorder: hypothesis and theory

A Densil, ME George, H Mahdi, A Chami… - Frontiers in Systems …, 2023 - frontiersin.org
The diagnostic process for psychiatric conditions is guided by the Diagnostic and Statistical
Manual of Mental Disorders (DSM) in North America. Revisions of the DSM over the years …

[HTML][HTML] Crafting Genetic Diversity: Unlocking the Potential of Protein Evolution

VK Gali, KL Tee, TS Wong - SynBio, 2024 - mdpi.com
Genetic diversity is the foundation of evolutionary resilience, adaptive potential, and the
flourishing vitality of living organisms, serving as the cornerstone for robust ecosystems and …

Synthesis of fluorinated amino acids by low-specificity, promiscuous aldolases coupled to in situ fluorodonor generation

A De Maria, M Nieto-Domínguez… - … Transport and Enzymatic …, 2024 - books.google.com
Synthesis of fluorinated amino acids by low-specificity, promiscuous aldolases coupled to in situ
fluorodonor generation Page 222 CHAPTER NINE Synthesis of fluorinated amino acids by …