Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …

The brain is a site of relative immune privilege. Although CD4 T cells have been reported in
the central nervous system, their presence in the healthy brain remains controversial, and …

Evidence supports the observational associations of gut microbiota with a variety of
psychiatric disorders, but the causal nature of such associations remains obscure. Aiming to …

Mounting evidence indicates that microglia, which are the resident immune cells of the brain,
play critical roles in a diverse array of neurodevelopmental processes required for proper …

Background: Several studies suggested an important role of the gut microbiota in the
pathophysiology of neurological disorders, implying that alteration of the gut microbiota …

Sleep deprivation (SD) is increasingly common in modern society, which can lead to the
dysregulation of inflammatory responses and cognitive impairment, but the mechanisms …

The gut and brain link via various metabolic and signalling pathways, each with the potential
to influence mental, brain and cognitive health. Over the past decade, the involvement of the …

Muconic acid is a bioprivileged molecule that can be converted into direct replacement
chemicals for incumbent petrochemicals and performance-advantaged bioproducts. In this …

Human diseases are increasingly linked with an altered or" dysbiotic" gut microbiota, but
whether such changes are causal, consequential, or bystanders to disease is, for the most …

Gut microbiome disturbances have been widely implicated in major depressive disorder
(MDD), although the identity of causal microbial species and the underlying mechanisms are …