Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …

Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor
malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for …

The gut microbiota is a vast, complex, and fascinating ecosystem of microorganisms that
resides in the human gastrointestinal tract. As an integral part of the microbiota–gut–brain …

Chronic ethanol exposure (CEE), which can lead to neuroinflammation, is an increasing risk
factor for depression disorder, but the underlying mechanism is not clear. Recent …

Neurodegenerative diseases are characterized by neuronal impairment and loss of function,
and with the major shared histopathological hallmarks of misfolding and aggregation of …

Gut bacteria face a key problem in how they capture enough energy to sustain their growth
and physiology. The gut bacterium Clostridium sporogenes obtains its energy by utilizing …

At the species level, immunity depends on the selection and transmission of protective
components of the immune system. A microbe-induced population of RORγ-expressing …

Autism spectrum disorder (ASD), a group of neurodevelopmental disorders characterized by
social communication deficits and stereotyped behaviors, may be associated with changes …

Background Autism spectrum disorder (ASD) is a neurodevelopmental condition with
hallmark behavioral manifestations including impaired social communication and restricted …

There is increasing evidence suggesting a link between the autism spectrum disorder (ASD)
and the gastrointestinal (GI) microbiome. Experimental and clinical studies have shown that …