Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis

MR Aburto, JF Cryan - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

[HTML][HTML] Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour

SF Henriques, DB Dhakan, L Serra… - Nature …, 2020 - nature.com
The impact of commensal bacteria on the host arises from complex microbial-diet-host
interactions. Mapping metabolic interactions in gut microbial communities is therefore key to …

You've got male: Sex and the microbiota-gut-brain axis across the lifespan

M Jaggar, K Rea, S Spichak, TG Dinan… - Frontiers in …, 2020 - Elsevier
Sex is a critical factor in the diagnosis and development of a number of mental health
disorders including autism, schizophrenia, depression, anxiety, Parkinson's disease …

[HTML][HTML] The developing microbiome from birth to 3 years: the gut-brain axis and neurodevelopmental outcomes

HE Laue, MO Coker, JC Madan - Frontiers in pediatrics, 2022 - frontiersin.org
The volume and breadth of research on the role of the microbiome in neurodevelopmental
and neuropsychiatric disorders has expanded greatly over the last decade, opening doors to …

Gut microbial signatures can discriminate unipolar from bipolar depression

P Zheng, J Yang, Y Li, J Wu, W Liang, B Yin… - Advanced …, 2020 - Wiley Online Library
Discriminating depressive episodes of bipolar disorder (BD) from major depressive disorder
(MDD) is a major clinical challenge. Recently, gut microbiome alterations are implicated in …

[HTML][HTML] The human gut microbiome as a potential factor in autism spectrum disorder

A Alharthi, S Alhazmi, N Alburae… - International journal of …, 2022 - mdpi.com
The high prevalence of gastrointestinal (GI) disorders among autism spectrum disorder
(ASD) patients has prompted scientists to look into the gut microbiota as a putative trigger in …

[HTML][HTML] A quantitative sequencing framework for absolute abundance measurements of mucosal and lumenal microbial communities

JT Barlow, SR Bogatyrev, RF Ismagilov - Nature communications, 2020 - nature.com
A fundamental goal in microbiome studies is determining which microbes affect host
physiology. Standard methods for determining changes in microbial taxa measure relative …

[HTML][HTML] Regulation of common neurological disorders by gut microbial metabolites

J Park, CH Kim - Experimental & Molecular Medicine, 2021 - nature.com
The gut is connected to the CNS by immunological mediators, lymphocytes,
neurotransmitters, microbes and microbial metabolites. A mounting body of evidence …

[HTML][HTML] The Microbiome-Gut-Brain axis regulates social cognition & craving in young binge drinkers

C Carbia, TFS Bastiaanssen, LF Iannone… - …, 2023 - thelancet.com
Background Binge drinking is the consumption of an excessive amount of alcohol in a short
period of time. This pattern of consumption is highly prevalent during the crucial …

The role of the probiotic Akkermansia muciniphila in brain functions: insights underpinning therapeutic potential

R Xu, Y Zhang, S Chen, Y Zeng, X Fu… - Critical reviews in …, 2023 - Taylor & Francis
The role of Akkermansia muciniphila, one of the most abundant microorganisms of the
intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity …