Calcitonin gene-related peptide (CGRP) is a neuropeptide with diverse physiological
functions. Its two isoforms (α and β) are widely expressed throughout the body in sensory …

The neuropeptides calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-
activating polypeptide (PACAP) have emerged as mediators of migraine pathogenesis. Both …

Background: Monoclonal antibodies (mAbs) against calcitonin gene-related peptides
(CGRP) are novel treatments for migraine prevention. Based on a previous functional …

Background Migraine is a disabling and chronic neurovascular headache disorder.
Trigeminal vascular activation and release of calcitonin gene-related peptide (CGRP) play a …

Targeting CGRP has proved to be efficacious, tolerable, and safe to treat migraine; however,
many patients with migraine do not benefit from drugs that antagonize the CGRPergic …

Background and Objectives Anti–calcitonin gene-related peptide (CGRP)(receptor)
antibodies are approved as preventive treatment for migraine. Recent concerns have been …

Objective We aimed (1) to analyze salivary calcitonin gene‐related peptide (CGRP) levels in
patients with migraine,(2) to predict erenumab response from baseline CGRP levels, and (3) …

The development of small-molecule calcitonin gene-related peptide (CGRP) receptor
antagonists (gepants) and of monoclonal antibodies targeting the CGRP system has been a …

Migraine afflicts more than 10% of the general population. Although its mechanism is poorly
understood, recent preclinical and clinical evidence has identified calcitonin gene related …

Skin immunity is regulated by many mediator molecules. One is the neuropeptide calcitonin
gene-related peptide (CGRP). CGRP has roles in regulating the function of components of …