Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation
M St Germain, R Iraji, M Bakovic - Frontiers in Nutrition, 2023 - frontiersin.org
Phosphatidylethanolamine is the major inner-membrane lipid in the plasma and
mitochondrial membranes. It is synthesized in the endoplasmic reticulum from ethanolamine …
mitochondrial membranes. It is synthesized in the endoplasmic reticulum from ethanolamine …
Cholesterol binds the amphipathic helix of IFITM3 and regulates antiviral activity
The interferon-induced transmembrane (IFITM) proteins broadly inhibit the entry of diverse
pathogenic viruses, including Influenza A virus (IAV), Zika virus, HIV-1, and SARS …
pathogenic viruses, including Influenza A virus (IAV), Zika virus, HIV-1, and SARS …
Kinetic relaxation of giant vesicles validates diffusional softening in a binary lipid mixture
The stiffness of biological membranes determines the work required by cellular machinery to
form and dismantle vesicles and other lipidic shapes. Model membrane stiffness can be …
form and dismantle vesicles and other lipidic shapes. Model membrane stiffness can be …
Simulated dynamic cholesterol redistribution favors membrane fusion pore constriction
Endo-and exocytosis proceed through a highly strained membrane fusion pore topology
regardless of the aiding protein machinery. The membrane's lipid components bias fusion …
regardless of the aiding protein machinery. The membrane's lipid components bias fusion …
Softening in two-component lipid mixtures by spontaneous curvature variance
The bending modulus of a lipid bilayer quantifies its mechanical resistance to curvature. It is
typically understood in terms of thickness; eg, thicker bilayers are usually stiffer. Here, we …
typically understood in terms of thickness; eg, thicker bilayers are usually stiffer. Here, we …
The full model of micropipette aspiration of cells: A mesoscopic simulation
Studies on the interaction between cells and micromanipulation tools are necessary to
optimize the procedures and improve the developmental potential of cells. The molecular …
optimize the procedures and improve the developmental potential of cells. The molecular …
The Role of Lipid Intrinsic Curvature in the Droplet Interface Bilayer
J Gudyka, J Ceja-Vega, M Krmic, R Porteus, S Lee - Langmuir, 2024 - ACS Publications
Model bilayers are constructed from lipids having different intrinsic curvatures using the
droplet interface bilayer (DIB) method, and their static physicochemical properties are …
droplet interface bilayer (DIB) method, and their static physicochemical properties are …
[PDF][PDF] MembraneAnalysis. jl: A Julia package for analyzing molecular dynamics simulations of lipid membranes
Biological membranes separate living cells from their surroundings, and, in case of
eukaryotes, partition the cell into its constituent organelles. These bilayer structures, which …
eukaryotes, partition the cell into its constituent organelles. These bilayer structures, which …
Curvature-induced lipid sorting beyond the critical packing parameter
Over the last few decades, the spatial organization of biomembranes has received a lot of
attention. With the fluid mosaic model, Singer and Nicolson proposed that biomembranes …
attention. With the fluid mosaic model, Singer and Nicolson proposed that biomembranes …
LEGO-lipophosphonoxins: length of hydrophobic module affects permeabilizing activity in target membranes of different phospholipid composition
M Dugić, H Brzobohatá, V Mojr, T Dolejšová… - RSC …, 2024 - pubs.rsc.org
In the past few decades, society has faced rapid development and spreading of
antimicrobial resistance due to antibiotic misuse and overuse and the immense adaptability …
antimicrobial resistance due to antibiotic misuse and overuse and the immense adaptability …