[HTML][HTML] Potassium channels in behavioral brain disorders. Molecular mechanisms and therapeutic potential: a narrative review.
Abstract Potassium channels (K+-channels) selectively control the passive flow of potassium
ions across biological membranes and thereby also regulate membrane excitability. Genetic …
ions across biological membranes and thereby also regulate membrane excitability. Genetic …
[HTML][HTML] The link between cognition and somatic conditions related to insulin resistance in the UK Biobank study cohort: a systematic review
Clinical and genomic studies have shown an overlap between neuropsychiatric disorders
and insulin resistance (IR)-related somatic conditions, including obesity, type 2 diabetes …
and insulin resistance (IR)-related somatic conditions, including obesity, type 2 diabetes …
Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders
The prevalence of somatic insulinopathies, like metabolic syndrome (MetS), obesity, and
type 2 diabetes mellitus (T2DM), is higher in Alzheimer's disease (AD), autism spectrum …
type 2 diabetes mellitus (T2DM), is higher in Alzheimer's disease (AD), autism spectrum …
Temporally ordered associations between type 2 diabetes and brain disorders–a Danish register-based cohort study
Background Type 2 diabetes mellitus (T2DM) is linked with several neurodegenerative and
psychiatric disorders, either as a comorbid condition or as a risk factor. We aimed to expand …
psychiatric disorders, either as a comorbid condition or as a risk factor. We aimed to expand …
A dimensional perspective on the genetics of obsessive-compulsive disorder
This review covers recent findings in the genomics of obsessive-compulsive disorder (OCD),
obsessive-compulsive symptoms, and related traits from a dimensional perspective. We …
obsessive-compulsive symptoms, and related traits from a dimensional perspective. We …
[HTML][HTML] A systematic review of preclinical studies exploring the role of insulin signalling in executive function and memory
AM Ottomana, M Presta, A O'Leary, M Sullivan… - … & biobehavioral reviews, 2023 - Elsevier
Beside its involvement in somatic dysfunctions, altered insulin signalling constitutes a risk
factor for the development of mental disorders like Alzheimer's disease and obsessive …
factor for the development of mental disorders like Alzheimer's disease and obsessive …
Obsessive compulsive disorder and response inhibition: Meta-analysis of the stop-signal task.
K Mar, P Townes, P Pechlivanoglou… - … and clinical science, 2022 - psycnet.apa.org
This systematic review and meta-analysis updates evidence pertaining to response
inhibition in obsessive–compulsive disorder (OCD) as measured by the stop-signal task …
inhibition in obsessive–compulsive disorder (OCD) as measured by the stop-signal task …
[HTML][HTML] Systematic review: molecular studies of common genetic variation in child and adolescent psychiatric disorders
WA Akingbuwa, AR Hammerschlag, M Bartels… - Journal of the American …, 2022 - Elsevier
Objective We conducted a systematic review of studies using molecular genetics and
statistical approaches to investigate the role of common genetic variation in the …
statistical approaches to investigate the role of common genetic variation in the …
[HTML][HTML] Insulin and disorders of behavioural flexibility
M Sullivan, F Fernandez-Aranda… - … & biobehavioral reviews, 2023 - Elsevier
Behavioural inflexibility is a symptom of neuropsychiatric and neurodegenerative disorders
such as Obsessive-Compulsive Disorder, Autism Spectrum Disorder and Alzheimer's …
such as Obsessive-Compulsive Disorder, Autism Spectrum Disorder and Alzheimer's …
Melancholic features and typical neurovegetative symptoms of major depressive disorder show specific polygenic patterns
Background Major depressive disorder (MDD) is a highly prevalent psychiatric condition
characterised by a heterogeneous clinical presentation and an estimated twin-based …
characterised by a heterogeneous clinical presentation and an estimated twin-based …