Emerging trends in the methodology of environmental toxicology: 3D cell culture and its applications

H Wang, T Xu, D Yin - Science of The Total Environment, 2023 - Elsevier
Human diseases and health concerns caused by environmental pollutants are globally
emerging. Therefore, rapid and efficient evaluation of the effects of environmental pollutants …

[HTML][HTML] The pollutome-connectome axis: a putative mechanism to explain pollution effects on neurodegeneration

L Pini, A Salvalaggio, AM Wennberg, A Dimakou… - Ageing Research …, 2023 - Elsevier
The study of pollutant effects is extremely important to address the epochal challenges we
are facing, where world populations are increasingly moving from rural to urban centers …

Neuro‐Glia‐Vascular‐on‐a‐Chip System to Assess Aggravated Neurodegeneration via Brain Endothelial Cells upon Exposure to Diesel Exhaust Particles

S Seo, M Jang, H Kim, JH Sung, N Choi… - Advanced Functional …, 2023 - Wiley Online Library
Air pollution induces neurodegeneration, including cognitive deficits, neuroinflammation,
and disruption of the blood–brain barrier. The mechanisms underlying air pollution …

[HTML][HTML] Toxicological Effects of Fine Particulate Matter (PM2.5): Health Risks and Associated Systemic Injuries—Systematic Review

A Garcia, E Santa-Helena, A De Falco… - Water, Air, & Soil …, 2023 - Springer
Previous studies focused on investigating particulate matter with aerodynamic diameter≤
2.5 µm (PM2. 5) have shown the risk of disease development, and association with …

Real-Time Quantification of Nanoplastics-Induced Oxidative Stress in Stretching Alveolar Cells

Y Zhao, WT Fan, KQ Jin, J Yan, YT Qi, WH Huang… - ACS …, 2024 - ACS Publications
Nanoplastics from air pollutants can be directly inhaled into the alveoli in the lungs and
further enter blood circulation, and numerous studies have revealed the close relation …

[HTML][HTML] Ambient fine particulate exposure and subcortical gray matter microarchitecture in 9-and 10-year-old children across the United States

K Sukumaran, C Cardenas-Iniguez, E Burnor… - IScience, 2023 - cell.com
Neuroimaging studies showing the adverse effects of air pollution on neurodevelopment
have largely focused on smaller samples from limited geographical locations and have …

[HTML][HTML] Long-term exposure to fine particulate matter and the risk of chronic liver diseases: a meta-analysis of observational studies

J Sui, H Xia, Q Zhao, G Sun, Y Cai - International Journal of …, 2022 - mdpi.com
Although fine particulate matter (PM2. 5) is a known carcinogen, evidence of the association
between PM2. 5 and chronic liver disease is controversial. In the present meta-analysis …

[HTML][HTML] HMGB1-NLRP3-P2X7R pathway participates in PM2. 5-induced hippocampal neuron impairment by regulating microglia activation

C Liu, Y She, J Huang, Y Liu, W Li, C Zhang… - Ecotoxicology and …, 2022 - Elsevier
Neuroinflammation is a key mechanism underlying the cognitive impairment induced by PM
2.5, and activated microglia plays an important role in this process. However, the …

Filtered air intervention modulates hypothalamic-pituitary-thyroid/gonadal axes by attenuating inflammatory responses in adult rats after fine particulate matter (PM2. 5 …

C Liu, J Yang, X Du, X Geng - Environmental Science and Pollution …, 2022 - Springer
We have previously reported that filtered air (FA) intervention reduces inflammation and
hypothalamus-pituitary-adrenal axis activation after fine particulate matter (PM2. 5 …

The role of ROS-pyroptosis in PM2. 5 induced air-blood barrier destruction

M Wei, Y Cong, J Lei, R Du, M Yang, X Lu… - Chemico-Biological …, 2023 - Elsevier
Abstract Fine particulate matter (PM 2.5) has attracted increasing attention due to its health-
threatening effects. Although numerous studies have investigated the impact of PM 2.5 on …