[HTML][HTML] Antiphospholipid Syndrome during pregnancy: the state of the art

FAF Di Prima, O Valenti, E Hyseni… - Journal of prenatal …, 2011 - ncbi.nlm.nih.gov
Obstetric complications are the hallmark of antiphospholipid syndrome. Recurrent
miscarriage, early delivery, oligohydramnios, prematurity, intrauterine growth restriction, fetal …

Catastrophic antiphospholipid syndrome

SK Vora, RA Asherson, D Erkan - Journal of intensive care …, 2006 - journals.sagepub.com
Catastrophic antiphospholipid syndrome is a rapidly progressive life-threatening disease
that causes multiple organ thromboses and dysfunction in the presence of antiphospholipid …

Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signaling pathways

A Lambrianides, CJ Carroll, SS Pierangeli… - The Journal of …, 2010 - journals.aai.org
A major mechanism of hypercoagulability in the antiphospholipid syndrome (APS) is
antiphospholipid Ab-mediated upregulation of tissue factor (TF) on monocytes via activation …

Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid …

EIB Peerschke, W Yin, DR Alpert, RAS Roubey… - Lupus, 2009 - journals.sagepub.com
Complement plays a major role in inflammation and thrombosis associated with systemic
lupus erythematosus (SLE) and the antiphospholipid syndrome (APS). A cross-sectional …

Lupus and the antiphospholipid syndrome in pregnancy and obstetrics: clinical characteristics, diagnosis, pathogenesis, and treatment

A Tincani, C Bazzani, S Zingarelli… - … in thrombosis and …, 2008 - thieme-connect.com
The antiphospholipid syndrome (APS) in pregnancy is associated with repeated
miscarriages and fetal loss. Other complications of pregnancy such as preeclampsia and …

What is antiphospholipid syndrome?

D Erkan, MD Lockshin - Current rheumatology reports, 2004 - Springer
The description of antiphospholipid syndrome (APS) is vascular thrombosis and/or
pregnancy morbidity occurring in persons with antiphospholipid antibodies (aPL). However …

The antiphospholipid syndrome

JH Rand - ASH Education Program Book, 2007 - ashpublications.org
The antiphospholipid syndrome (APS) is an autoimmune thrombophilic condition that is
marked by the presence of antibodies that recognize phospholipid-binding proteins. The …

Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome

C Pericleous, LA Clarke, PA Brogan… - Thrombosis and …, 2013 - thieme-connect.com
IgG antiphospholipid antibodies (aPL) exert direct effects on various cell types, contributing
to the pathogenesis of thrombosis and pregnancy morbidity in patients with the …

Therapeutic potential of toleragens in the management of antiphospholipid syndrome

KA Cockerill, GM Iverson, DS Jones, MD Linnik - BioDrugs, 2004 - Springer
Autoantibodies to β2-glycoprotein I (β2GPI) are believed to be the primary cause of
coagulation abnormalities in patients with antiphospholipid syndrome (APS). Clinical …

Arginine residues are important in determining the binding of human monoclonal antiphospholipid antibodies to clinically relevant antigens

I Giles, N Lambrianides, N Pattni, D Faulkes… - The Journal of …, 2006 - journals.aai.org
In the antiphospholipid syndrome (APS), antiphospholipid Abs (aPL) bind to anionic
phospholipids (PL) and various associated proteins, especially β 2-glycoprotein I (β2GPI) …