The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin

I Giles, N Lambrianides, D Latchman, P Chen… - Arthritis Res Ther, 2004 - Springer
Previously we reported that the variable heavy chain region (VH) of a human beta 2
glycoprotein I-dependent monoclonal antiphospholipid antibody (IS4) was dominant in …

Ehlers-Danlos syndrome type IV in a young man.

RA Asherson, C Bosman, M Tikly, F Spiro… - The Journal of …, 2006 - jrheum.org
We describe a 19-year-old male, with a family history of both systemic lupus erythematosus
and Marfan syndrome, who had a history of bruising easily and skin lesions since childhood …

Antiphospholipid antibody syndrome: the flow cytometric annexin A5 competition assay as a diagnostic tool

A Tomer, S Bar‐Lev, S Fleisher… - British journal of …, 2007 - Wiley Online Library
The mechanism underlying hypercoagulability in antiphospholipid antibody syndrome (APS)
is uncertain. Here, we present a flow‐cytometric assay (FCA) based on the hypothesis that …

Do antiphospholipid antibodies have direct pathologic effects upon endometrial and trophoblast cells?

C Pericleous, A Rahman, I Giles - Current Rheumatology …, 2009 - ingentaconnect.com
The presence of antiphospholipid antibodies (aPL) in association with vascular thromboses
(VT) and/or pregnancy morbidity (PM) is the hallmark of the Antiphospholipid Syndrome …

Das Antiphospholipid-Syndrom

W Miesbach, I Scharrer - DMW-Deutsche Medizinische …, 2004 - thieme-connect.com
Antiphospholipid antibody syndrome (APS) is characterised by the presence of frequently
recurring venous and/or arterial thrombosis, abortions and repeated evidence of lupus …

Trombose do sistema venoso porta após o parto numa doente com Síndrome de Anticorpos Antifosfolipídos

C Veríssimo, T Matos… - Acta Médica …, 2010 - repositorio.hff.min-saude.pt
Introdução: A síndrome de anticorpos antifosfolípidos (SAAF) é uma trombofilia autoimune
de etiologia mal definida e que condiciona tromboses vasculares e complicações …

[PDF][PDF] Neurological manifestations in the anti-phospholipid syndrome

IM Cojocaru - Türk Biyokimya Dergisi [Turkish Journal of …, 2010 - researchgate.net
Neurological manifestations are prominent and common in patients with autoimmune
condition anti-phospholipid (Hughes) syndrome (APS) which can affect people of any age …

Antiphospholipid Syndrome in the Older Population

SS Pierangeli, AM Seif, EB González - Geriatric Rheumatology: A …, 2011 - Springer
The syndrome of the black swan was first described following a unique case of recurrent
venous thrombosis, fetal loss, and the presence of anticardiolipin (aCL) antibodies more …

[PDF][PDF] Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signalling pathways1

CJ Carroll, SS Pierangeli, C Pericleous, W Branch… - J Immunol, 2010 - academia.edu
A major mechanism of hypercoagulability in the antiphospholipid syndrome (APS) is
antiphospholipid antibody (aPL)-mediated up-regulation of tissue factor (TF) on monocytes …

[引用][C] Síndrome antifosfolipídico

R Cervera, M Rodríguez-Mahou - Majadahonda: Ergon, 2007