Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with a poor prognosis
and limited treatment options. Many compounds have shown efficacy in preclinical models …

Background Crystalline silica (cSiO2) is a mineral found in rocks; workers from the
construction or denim industries are particularly exposed to cSiO2 through inhalation. cSiO2 …

Background Fibroblasts have important roles in the synthesis and remodeling of
extracellular matrix (ECM) proteins during pulmonary fibrosis. However, the spatiotemporal …

Pulmonary fibrosis (PF) is an intractable disorder with a poor prognosis. Although lung
fibroblasts play a central role in PF, the key regulatory molecules involved in this process …

Genomic selection has been widely implemented in many livestock breeding programs, but
it remains incipient in buffalo. Therefore, this study aimed to (1) estimate variance …

Objective: The present study was conducted to determine the role of gremlin during the
development of posterior capsular opacification (PCO) via in vitro and in vivo experiments …

Ethnopharmacological relevance Ginkgo biloba L. is a kind of traditional Chinese medicinal
material with a long history. Its main active ingredients, ginkgolides, can be used for the …

Sonic hedgehog (SHH) signaling is an important promotor of desmoplasia, a critical feature
in pancreatic cancer stromal reactions involving the activation of pancreatic stellate cells …

Bone morphogenetic proteins (BMPs) are multifunctional secreted cytokines that act in a
highly context-dependent manner. BMP action extends beyond the induction of cartilage …

Bone morphogenetic protein (BMP) signaling is required for early forebrain development
and cortical formation. How the endogenous modulators of BMP signaling regulate the …