miR-429 suppresses tumor migration and invasion by targeting CRKL in hepatocellular carcinoma via inhibiting Raf/MEK/ERK pathway and epithelial-mesenchymal …

C Guo, D Zhao, Q Zhang, S Liu, MZ Sun - Scientific reports, 2018 - nature.com
Tumor metastasis is one of the main causes of hepatocellular carcinoma (HCC) high
mortality. CRKL (v-crk sarcoma virus CT10 oncogene homologue (avian)-like) play …

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate

C Clarke, M Henry, P Doolan, S Kelly, S Aherne… - BMC genomics, 2012 - Springer
Background To study the role of microRNA (miRNA) in the regulation of Chinese hamster
ovary (CHO) cell growth, qPCR, microarray and quantitative LC-MS/MS analysis were …

MiRNA-497 regulates cell growth and invasion by targeting cyclin E1 in breast cancer

Q Luo, X Li, Y Gao, Y Long, L Chen, Y Huang… - Cancer cell …, 2013 - Springer
Background MicroRNAs are a class of endogenous single strand non-coding RNAs that are
involved in many important physiological and pathological processes. The purpose of this …

Silencing of lncRNA MIR497HG via CRISPR/Cas13d induces bladder cancer progression through promoting the crosstalk between Hippo/Yap and TGF-β/Smad …

C Zhuang, Y Liu, S Fu, C Yuan, J Luo… - Frontiers in Molecular …, 2020 - frontiersin.org
A subset of long non-coding RNAs (lncRNAs), categorized as miRNA-host gene lncRNAs
(lnc-miRHGs), is processed to produce miRNAs and involved in cancer progression. This …

Circulating miR-106a is a novel prognostic and lymph node metastasis indicator for cholangiocarcinoma

Q Cheng, F Feng, L Zhu, Y Zheng, X Luo, C Liu, B Yi… - Scientific Reports, 2015 - nature.com
Cholangiocarcinoma (CCA) is a common biliary malignancy. Despite continuing advances,
novel indicators are urgently needed to identify patients with a poor prognosis. Several …

Micro RNA‐379 suppresses osteosarcoma progression by targeting PDK 1

Z Li, J Shen, MTV Chan, WKK Wu - Journal of cellular and …, 2017 - Wiley Online Library
Osteosarcoma is the most common primary bone tumour. Increasing evidence has
demonstrated the pathogenic role of micro RNA (mi RNA s) dysregulation in tumour …

miRNA expression changes during the course of neoadjuvant bevacizumab and chemotherapy treatment in breast cancer

EM Lindholm, M Ragle Aure, MH Haugen… - Molecular …, 2019 - Wiley Online Library
One of the hallmarks of cancer is sustained angiogenesis. Favorable results have been
reported in some breast cancer (BC) patients receiving antiangiogenic therapy with …

[HTML][HTML] miR-497-5p inhibits cell proliferation and invasion by targeting KCa3. 1 in angiosarcoma

Y Chen, D Kuang, X Zhao, D Chen, X Wang, Q Yang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Angiosarcoma is a rare malignant mesenchymal tumor with poor prognosis. We aimed to
identify malignancy-associated miRNAs and their target genes, and explore biological …

MicroRNA-377 suppresses cell proliferation and invasion by inhibiting TIAM1 expression in hepatocellular carcinoma

G Chen, L Lu, C Liu, L Shan, D Yuan - PloS one, 2015 - journals.plos.org
Increasing evidence has suggested that microRNAs (miRNAs) play an important role in the
initiation and progression of hepatocellular carcinoma (HCC). Here, we identified a novel …

[HTML][HTML] miR-497 expression, function and clinical application in cancer

G Yang, G Xiong, Z Cao, S Zheng, L You, T Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs that inhibit gene expression by binding to
the 3′ untranslated region (3′-UTR) of their target mRNAs. Recent studies show that miR …