Fifteen recommendations and a therapeutic algorithm regarding the management of acute
respiratory distress syndrome (ARDS) at the early phase in adults are proposed. The Grade …

Objective: To update the 2002 version of “Clinical practice guidelines for sustained
neuromuscular blockade in the adult critically ill patient.” Design: A Task Force comprising …

Background: This document provides evidence-based clinical practice guidelines on the use
of mechanical ventilation in adult patients with acute respiratory distress syndrome (ARDS) …

The Faculty of Intensive Care Medicine and Intensive Care Society Guideline Development
Group have used GRADE methodology to make the following recommendations for the …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Objective: To provide an update to the “Surviving Sepsis Campaign Guidelines for
Management of Severe Sepsis and Septic Shock,” last published in 2008. Design: A …

Introduction Randomized trials investigating neuromuscular blocking agents in adult acute
respiratory distress syndrome (ARDS) have been inconclusive about effects on mortality …

Introduction Small-study effects refer to the fact that trials with limited sample sizes are more
likely to report larger beneficial effects than large trials. However, this has never been …

Rationale: Trials investigating use of lower tidal volumes and inspiratory pressures for
patients with acute respiratory distress syndrome (ARDS) have shown mixed results …

The timing of extracorporeal membrane oxygenation (ECMO) initiation and its outcome in
the management of respiratory and cardiac failure have received considerable attention, but …