Vascular and lymphatic malformations represent a challenge for clinicians. The identification
of inherited and somatic mutations in important signaling pathways, including the PI3K …

Vascular Malformations belong to the spectrum of orphan diseases and can involve all
segments of the vascular tree: arteries, capillaries, and veins, and similarly the lymphatic …

Low‐flow vascular malformations are congenital overgrowths composed of abnormal blood
vessels potentially causing pain, bleeding and obstruction of different organs. These …

Hereditary hemorrhagic telangiectasia (HHT), also known as Osler–Weber–Rendu disease,
is a rare disorder with a case prevalence as high as one in 5000, causing arteriovenous …

The formation of vascular networks consisting of arteries, capillaries, and veins is vital in
embryogenesis. It is also crucial in adulthood for the formation of a functional vasculature …

Saphenous vein bypass grafting is an effective technique used to treat peripheral arterial
disease (PAD). However, restenosis is the major clinical challenge for the graft vessel …

During blood vessel development, endothelial cells become specified toward arterial or
venous fates to generate a circulatory network that provides nutrients and oxygen to, and …

Vascular malformations are anomalies in vascular development that portend a significant
risk of hemorrhage, morbidity and mortality. Conventional treatments with surgery …

Purpose: Vascular anomalies are a heterogeneous group of disorders that frequently
present in the periorbital region. They encompass 2 broad entities: vascular tumors, which …

Venous malformation (VM) and cavernous venous malformation (CVM) are two types of
vascular malformations. Even if the two diseases are similar in appearance and imaging, the …