All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Macrophages are a diverse set of cells present in all body compartments. This diversity is
imprinted by their ontogenetic origin (embryonal versus adult bone marrow–derived cells); …

Abstract Aims Mesenchymal stromal cells (MSCs) gradually become attractive candidates
for cardiac inflammation modulation, yet understanding of the mechanism remains elusive …

This mini-review summarizes the current evidence for the role of macrophage activation and
polarization in inflammation and immune response pertinent to interstitial lung disease …

Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …

Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

Monocytes and macrophages are important components of the immune system, specialized
in either removing pathogens as part of innate immunity or contributing to adaptive immunity …

Macrophages are cells of the innate immunity constituting the mononuclear phagocyte
system and endowed with remarkable different roles essential for defense mechanisms …

Background Within the last few years, it has become evident that LPS-preconditioned
mesenchymal stromal cells (LPS pre-MSCs) show enhanced paracrine effects, including …

Rationale: Differential activation of macrophages correlates closely with tumor progression,
and the epigenetic factor lysine demethylase 6B (KDM6B, previously named JMJD3) …