[HTML][HTML] Radiotherapy combined with immunotherapy: the dawn of cancer treatment

Z Zhang, X Liu, D Chen, J Yu - Signal transduction and targeted …, 2022 - nature.com
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …

Radiotherapy toxicity

D De Ruysscher, G Niedermann, NG Burnet… - Nature Reviews …, 2019 - nature.com
Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

ZBP1-MLKL necroptotic signaling potentiates radiation-induced antitumor immunity via intratumoral STING pathway activation

Y Yang, M Wu, D Cao, C Yang, J Jin, L Wu, X Hong… - Science …, 2021 - science.org
Necroptosis, a form of regulated necrosis, participates in tumor development and dying cell
immunogenicity. However, it remains unclear how tumor cell–intrinsic necroptotic signaling …

[HTML][HTML] Localized nuclear reaction breaks boron drug capsules loaded with immune adjuvants for cancer immunotherapy

Y Shi, Z Guo, Q Fu, X Shen, Z Zhang, W Sun… - Nature …, 2023 - nature.com
Boron neutron capture therapy (BNCT) was clinically approved in 2020 and exhibits
remarkable tumour rejection in preclinical and clinical studies. It is binary radiotherapy that …

Magnetic nanoparticles for cancer theranostics: Advances and prospects

X Li, W Li, M Wang, Z Liao - Journal of Controlled Release, 2021 - Elsevier
Cancer is one of the leading causes of mortality worldwide. Nanoparticles have been
broadly studied and emerged as a novel approach in diagnosis and treatment of tumors …

Efficacy and safety of transarterial chemoembolization plus external beam radiotherapy vs sorafenib in hepatocellular carcinoma with macroscopic vascular invasion …

SM Yoon, BY Ryoo, SJ Lee, JH Kim, JH Shin… - JAMA …, 2018 - jamanetwork.com
Importance Patients with hepatocellular carcinoma showing macroscopic vascular invasion
have a poor prognosis. Sorafenib is the sole treatment option for these patients, with …

[HTML][HTML] Effects and mechanisms of curcumin for the prevention and management of cancers: An updated review

ZJ Yang, SY Huang, DD Zhou, RG Xiong, CN Zhao… - Antioxidants, 2022 - mdpi.com
Cancer is the leading cause of death in the world. Curcumin is the main ingredient in
turmeric (Curcuma longa L.), and is widely used in the food industry. It shows anticancer …

[HTML][HTML] Circadian rhythms and cancers: the intrinsic links and therapeutic potentials

L Zhou, Z Zhang, E Nice, C Huang, W Zhang… - Journal of Hematology & …, 2022 - Springer
The circadian rhythm is an evolutionarily conserved time-keeping system that comprises a
wide variety of processes including sleep–wake cycles, eating–fasting cycles, and activity …

Cold atmospheric plasma delivery for biomedical applications

Z Chen, G Chen, R Obenchain, R Zhang, F Bai, T Fang… - materials today, 2022 - Elsevier
As the fourth state of matter, plasma's unique properties and interactions with other states of
matter offer many promising opportunities for investigation and discovery. In particular, cold …

[HTML][HTML] Identification and characterization of Cardiac Glycosides as senolytic compounds

F Triana-Martínez, P Picallos-Rabina… - Nature …, 2019 - nature.com
Compounds with specific cytotoxic activity in senescent cells, or senolytics, support the
causal involvement of senescence in aging and offer therapeutic interventions. Here we …