IGF-1 and cardiovascular disease

Y Higashi, S Gautam, P Delafontaine… - Growth Hormone & IGF …, 2019 - Elsevier
Atherosclerosis is an inflammatory arterial pathogenic condition, which leads to ischemic
cardiovascular diseases, such as coronary artery disease and myocardial infarction, stroke …

The role of IGF/IGF-1R signaling in hepatocellular carcinomas: stemness-related properties and drug resistance

MHT Ngo, HY Jeng, YC Kuo, JD Nanda… - International journal of …, 2021 - mdpi.com
Insulin-like Growth Factor (IGF)/IGF-1 Receptor (IGF-1R) signaling is known to regulate stem
cell pluripotency and differentiation to trigger cell proliferation, organ development, and …

Ovarian rejuvenation through platelet-rich autologous plasma (PRP)—a chance to have a baby without donor eggs, improving the life quality of women suffering from …

N Petryk, M Petryk - Reproductive Sciences, 2020 - Springer
Due to the fact that modern American and European women postpone childbirth until later in
life, they are more likely to face the problem of ovarian insufficiency by the time they are …

Ovarian follicular dynamics, progesterone concentrations, pregnancy rates and transcriptional patterns in Bos indicus females with a high or low antral follicle count

MA de Lima, F Morotti, BM Bayeux, RG de Rezende… - Scientific reports, 2020 - nature.com
We evaluated the effect of the antral follicle count (AFC) on ovarian follicular dynamics,
pregnancy rates, progesterone concentrations, and transcriptional patterns of genes in …

Multiomics Analyses Provide New Insight into Genetic Variation of Reproductive Adaptability in Tibetan Sheep

B Han, D Tian, X Li, S Liu, F Tian, D Liu… - Molecular Biology …, 2024 - academic.oup.com
Domestication and artificial selection during production-oriented breeding have greatly
shaped the level of genomic variability in sheep. However, the genetic variation associated …

Progressive changes in human follicular fluid composition over the course of ovulation: quantitative proteomic analyses

L la Cour Poulsen, I Pla, A Sanchez… - Molecular and cellular …, 2019 - Elsevier
Follicular fluid (FF) acts as a vehicle for paracrine signalling between somatic cells of the
follicle and the oocyte. To investigate changes in the protein composition of FF during …

Identification of genes involved in chicken follicle selection by ONT sequencing on granulosa cells

D Li, C Zhong, Y Sun, L Kang, Y Jiang - Frontiers in Genetics, 2023 - frontiersin.org
In chickens, follicle selection is an important process affecting laying traits, which is
characterized by the differentiation of granulosa cells and the synthesis of progesterone by …

Proteome of fluid from human ovarian small antral follicles reveals insights in folliculogenesis and oocyte maturation

I Pla, A Sanchez, SE Pors, K Pawlowski… - Human …, 2021 - academic.oup.com
STUDY QUESTION Is it possible to identify by mass spectrometry a wider range of proteins
and key proteins involved in folliculogenesis and oocyte growth and development by …

Pregnancy-associated plasma protein-A in atherosclerosis: molecular marker, mechanistic insight, and therapeutic target

XH Yu, LH He, JH Gao, DW Zhang, XL Zheng, CK Tang - Atherosclerosis, 2018 - Elsevier
Pregnancy-associated plasma protein-A (PAPP-A), a member of the metzincin
metalloproteinase superfamily, can enhance local insulin-like growth factor (IGF) …

[HTML][HTML] Effects of adjuvant growth hormone therapy on poor ovarian responders in assisted reproductive technology

S Zafardoust, S Ansaripor, A Karimi, H Hosseinirad… - Maedica, 2022 - ncbi.nlm.nih.gov
Objective: The present study aimed to evaluate the effect of adjuvant growth hormone (GH)
therapy in antagonist protocol aiming to improve ovarian response and clinical outcomes of …