NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications

C Jiang, H Huang, X Kang, L Yang, Z Xi… - Chemical Society …, 2021 - pubs.rsc.org
Compounds with a nitrobenzoxadiazole (NBD) skeleton exhibit prominent useful properties
including environmental sensitivity, high reactivity toward amines and biothiols (including …

[HTML][HTML] The role of amino acids in neurotransmission and fluorescent tools for their detection

R Dalangin, A Kim, RE Campbell - International journal of molecular …, 2020 - mdpi.com
Neurotransmission between neurons, which can occur over the span of a few milliseconds,
relies on the controlled release of small molecule neurotransmitters, many of which are …

Near-infrared fluorescent probe with large stokes shift for imaging of hydrogen sulfide in tumor-bearing mice

L Yan, QS Gu, WL Jiang, M Tan, ZK Tan… - Analytical …, 2022 - ACS Publications
Hydrogen sulfide (H2S) is an important endogenous gas signal molecule in living system,
which participates in a variety of physiological processes. Very recent evidence has …

Nitric oxide and redox mechanisms in the immune response

DA Wink, HB Hines, RYS Cheng… - Journal of leukocyte …, 2011 - academic.oup.com
The role of redox molecules, such as NO and ROS, as key mediators of immunity has
recently garnered renewed interest and appreciation. To regulate immune responses, these …

Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders

V Calabrese, C Cornelius… - Antioxidants & redox …, 2010 - liebertpub.com
Despite the capacity of chaperones and other homeostatic components to restore folding
equilibrium, cells appear poorly adapted for chronic oxidative stress that increases in cancer …

Hydrogen sulfide and cell signaling

L Li, P Rose, PK Moore - Annual review of pharmacology and …, 2011 - annualreviews.org
Hydrogen sulfide (H2S) is a gaseous mediator synthesized from cysteine by cystathionine γ
lyase (CSE) and other naturally occurring enzymes. Pharmacological experiments using …

Making and working with hydrogen sulfide: the chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a review

MN Hughes, MN Centelles, KP Moore - Free Radical Biology and Medicine, 2009 - Elsevier
Hydrogen sulfide is rapidly emerging as an important vasoactive mediator formed in health
and disease. Its biological action is centered on its reactivity with heme-proteins and its …

Dealing with methionine/homocysteine sulfur: cysteine metabolism to taurine and inorganic sulfur

MH Stipanuk, I Ueki - Journal of inherited metabolic disease, 2011 - Springer
Synthesis of cysteine as a product of the transsulfuration pathway can be viewed as part of
methionine or homocysteine degradation, with cysteine being the vehicle for sulfur …

Selective turn-on fluorescent probes for imaging hydrogen sulfide in living cells

LA Montoya, MD Pluth - Chemical communications, 2012 - pubs.rsc.org
Hydrogen sulfide (H2S) is an important biological messenger but few biologically-
compatible methods are available for its detection. Here we report two bright fluorescent …

An endoplasmic reticulum-targeted ratiometric fluorescent probe for the sensing of hydrogen sulfide in living cells and zebrafish

W Shu, S Zang, C Wang, M Gao, J Jing… - Analytical …, 2020 - ACS Publications
Hydrogen sulfide (H2S) is an endogenous gaseous signaling molecule in many
physiological processes. Relevant investigations indicated that H2S plays a cytoprotective …