FSP1: a key regulator of ferroptosis

W Li, L Liang, S Liu, H Yi, Y Zhou - Trends in Molecular Medicine, 2023 - cell.com
Abstract Ferroptosis suppressor protein 1 (FSP1) is one of the main regulatory molecules of
ferroptosis. FSP1 functions through the FSP1-coenzyme Q10 (CoQ10)-NAD (P) H axis and …

Fat-soluble vitamins: updated review of their role and orchestration in human nutrition throughout life cycle with sex differences

RA Youness, A Dawoud, O ElTahtawy, MA Farag - Nutrition & Metabolism, 2022 - Springer
Age and Gender are vital determinants for the micronutrient demands of normal indviduals.
Among these micronutrients are vitamins that are required in small amounts for optimum …

Diverse biological functions of vitamin K: from coagulation to ferroptosis

E Mishima, A Wahida, T Seibt, M Conrad - Nature metabolism, 2023 - nature.com
Vitamin K is essential for several physiological processes, such as blood coagulation, in
which it serves as a cofactor for the conversion of peptide-bound glutamate to γ …

New insights into vitamin K biology with relevance to cancer

JE Welsh, MJ Bak, CJ Narvaez - Trends in molecular medicine, 2022 - cell.com
Phylloquinone (vitamin K1) and menaquinones (vitamin K2 family) are essential for post-
translational γ-carboxylation of a small number of proteins, including clotting factors. These …

Personalized medicine in mitochondrial health and disease: molecular basis of therapeutic approaches based on nutritional supplements and their analogs

V Tragni, G Primiano, A Tummolo, L Cafferati Beltrame… - Molecules, 2022 - mdpi.com
Mitochondrial diseases (MDs) may result from mutations affecting nuclear or mitochondrial
genes, encoding mitochondrial proteins, or non-protein-coding mitochondrial RNA. Despite …

Improving cognitive function with nutritional supplements in aging: a comprehensive narrative review of clinical studies investigating the effects of vitamins, minerals …

M Fekete, A Lehoczki, S Tarantini, V Fazekas-Pongor… - Nutrients, 2023 - mdpi.com
Cognitive impairment and dementia are burgeoning public health concerns, especially
given the increasing longevity of the global population. These conditions not only affect the …

Integrated microfluidic devices for point-of-care detection of bio-analytes and disease

PP Behera, N Kumar, M Kumari, S Kumar… - Sensors & …, 2023 - pubs.rsc.org
Micro-and nanofluidics have enabled the possibility of miniaturized analytical systems,
which are commonly known as lab-on-a-chip (LOC) devices. One of the clear benefits of …

Vitamins as regulators of calcium-containing kidney stones—new perspectives on the role of the gut microbiome

JA Chmiel, GA Stuivenberg, KF Al, PP Akouris… - Nature Reviews …, 2023 - nature.com
Calcium-based kidney stone disease is a highly prevalent and morbid condition, with an
often complicated and multifactorial aetiology. An abundance of research on the role of …

Links between vitamin K, ferroptosis and SARS-CoV-2 infection

J Nuszkiewicz, P Sutkowy, M Wróblewski… - Antioxidants, 2023 - mdpi.com
Ferroptosis is a recently discovered form of programmed cell death. It is characterized by the
accumulation of iron and lipid hydroperoxides in cells. Vitamin K is known to have …

Role of vitamin K in chronic kidney disease: A focus on bone and cardiovascular health

F Bellone, M Cinquegrani, R Nicotera… - International Journal of …, 2022 - mdpi.com
Chronic kidney disease (CKD) is commonly associated with vitamin K deficiency. Some of
the serious complications of CKD are represented by cardiovascular disease (CVD) and …