Macrophages are one of the most important cells in the innate immune system, they are
converted into two distinct subtypes with completely different molecular phenotypes and …

The characteristics of monocyte/macrophage lineage are diversity and plasticity, mainly
manifested by M1 and M2 subtypes in the body tissues, and playing different roles in the …

Viral infections present significant challenges to human health, underscoring the importance
of understanding the immune response for effective therapeutic strategies. Immune cell …

Macrophage polarization is a dynamic process determining the outcome of various
physiological and pathological situations through inducing pro-inflammatory responses or …

Self-tolerance involves protection from self-reactive B and T cells via negative selection
during differentiation, programmed cell death, and inhibition of regulatory T cells. The …

Novel treatment targets must be discovered to improve the results for patients with prostate
cancer, which continues to be a significant worldwide health problem. Growth Arrest-Specific …

Leishmania infantum, the etiological agent of canine leishmaniosis (CanL) in Europe, was
responsible of the largest outbreak of human leishmaniosis in Spain. The parasite infects …

Macrophages are a heterogeneous cell type with high plasticity, exhibiting unique activation
characteristics that modulate the progression and resolution of diseases, serving as a key …

Macrophages are highly heterogeneous and plastic immune cells that play an important role
in the fight against pathogenic microorganisms and tumor cells. After different stimuli …

Single‐cell microRNA (miRNA) sequencing has allowed for comprehensively studying the
abundance and complex networks of miRNAs, which provides insights beyond single‐cell …