Engineering nanomedicine for glutathione depletion-augmented cancer therapy

Y Xiong, C Xiao, Z Li, X Yang - Chemical Society Reviews, 2021 - pubs.rsc.org
Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

Metal–Organic Frameworks (MOF)-Assisted Sonodynamic Therapy in Anticancer Applications

F Yang, J Dong, Z Li, Z Wang - ACS nano, 2023 - ACS Publications
Sonodynamic therapy (SDT) has emerged as a promising therapeutic modality for
anticancer treatments and is becoming a cutting-edge interdisciplinary research field. This …

Conferring Ti‐based MOFs with defects for enhanced sonodynamic cancer therapy

S Liang, X Xiao, L Bai, B Liu, M Yuan, P Ma… - Advanced …, 2021 - Wiley Online Library
The development of highly efficient, multifunctional, and biocompatible sonosensitizer is still
a priority for current sonodynamic therapy (SDT). Herein, a defect‐rich Ti‐based metal …

Advances and perspectives in organic sonosensitizers for sonodynamic therapy

X Xing, S Zhao, T Xu, L Huang, Y Zhang, M Lan… - Coordination Chemistry …, 2021 - Elsevier
Sonodynamic therapy (SDT), which involves a combination of low-intensity ultrasound (US)
and a chemical sonosensitizer, has emerged as a promising minimally invasive and …

Ultrasmall iron-doped titanium oxide nanodots for enhanced sonodynamic and chemodynamic cancer therapy

S Bai, N Yang, X Wang, F Gong, Z Dong, Y Gong… - ACS …, 2020 - ACS Publications
Sonodynamic therapy (SDT), which can generate reactive oxygen species (ROS) based on
sonosensitizers under ultrasound (US) to kill tumor cells, has emerged as a noninvasive …

Rational design of platinum–bismuth sulfide Schottky heterostructure for sonocatalysis‐mediated hydrogen therapy

M Yuan, S Liang, L Yang, F Li, B Liu, C Yang… - Advanced …, 2023 - Wiley Online Library
Conventional sonodynamic therapy is unavoidably limited by the tumor microenvironment,
although many sonosensitizers have been developed to improve them to a certain extent …

Cancer cell membrane-coated C-TiO2 hollow nanoshells for combined sonodynamic and hypoxia-activated chemotherapy

S Ning, X Dai, W Tang, Q Guo, M Lyu, D Zhu, W Zhang… - Acta biomaterialia, 2022 - Elsevier
Sonodynamic therapy (SDT) is a promising strategy for tumor treatment that satisfies all
requirements of penetrating deep-seated tissues without causing additional trauma …

A robust narrow bandgap vanadium tetrasulfide sonosensitizer optimized by charge separation engineering for enhanced sonodynamic cancer therapy

S Liang, B Liu, X Xiao, M Yuan, L Yang… - Advanced …, 2021 - Wiley Online Library
The development and optimization of sonosensitizers for elevating intratumoral reactive
oxygen species (ROS) are definitely appealing in current sonodynamic therapy (SDT). Given …

Achieving Fast Charge separation by ferroelectric ultrasonic interfacial engineering for rapid sonotherapy of bacteria‐infected osteomyelitis

J Li, X Liu, Y Zheng, Z Cui, H Jiang, Z Li… - Advanced …, 2023 - Wiley Online Library
Bacteria‐infected osteomyelitis is life‐threatening without effective therapeutic methods
clinically. Here, a rapid and effective therapeutic strategy to treat osteomyelitis through …

Continuous inertial cavitation evokes massive ROS for reinforcing sonodynamic therapy and immunogenic cell death against breast carcinoma

Y Yin, X Jiang, L Sun, H Li, C Su, Y Zhang, G Xu, X Li… - Nano Today, 2021 - Elsevier
Intratumoral immunosuppressive microenvironment (ISM) remains the dominant limitation to
disable oncological immunotherapy such as immunogenic cell death (ICD). To resolve the …