Update on applications and limitations of perioperative tranexamic acid

PA Patel, JA Wyrobek, AJ Butwick… - Anesthesia & …, 2022 - journals.lww.com
Tranexamic acid (TXA) is a potent antifibrinolytic with documented efficacy in reducing blood
loss and allogeneic red blood cell transfusion in several clinical settings. With a growing …

Utilization of tranexamic acid in surgical orthopaedic practice: indications and current considerations

A Haratian, T Shelby, LK Hasan, IK Bolia… - Orthopedic Research …, 2021 - Taylor & Francis
Tranexamic acid (TXA) is a lysine analog that exhibits an anti-fibrinolytic effect by directly
preventing the activation of plasminogen as well as inhibiting activated plasmin from …

Guidelines on perioperative optimization protocol for the adult patient 2023

S Bloc, P Alfonsi, A Belbachir, M Beaussier… - … Critical Care & Pain …, 2023 - Elsevier
Abstract Objective The French Society of Anesthesiology and Intensive Care Medicine
[Société Française d'Anesthésie et de Réanimation (SFAR)] aimed at providing guidelines …

Chinese clinical practice guidelines in treating knee osteoarthritis by periarticular knee osteotomy

X Ma, Y Hu, K Wang… - Orthopaedic …, 2022 - Wiley Online Library
Unicompartmental knee osteoarthritis (UKOA) is the early stage of knee joint degeneration,
which is characterized by unicompartmental degeneration and mostly occurs in medial …

Tranexamic acid in combination with vancomycin or gentamicin has a synergistic effect against Staphylococci

A Benjumea, M Díaz-Navarro, R Hafian… - Frontiers in …, 2022 - frontiersin.org
Background Tranexamic acid (TXA) is an antifibrinolytic agent applied in orthopedic surgery
and has been proven to reduce post-surgery infection rates. We previously showed that TXA …

Double level osteotomy for medial osteoarthritis and bifocal varus malalignment has excellent short-term results while maintaining physiologic radiographic joint …

P Schuster, F Rathgeb, P Mayer, S Michalski… - Knee Surgery, Sports …, 2023 - Springer
Purpose The purpose of this study was to prospectively evaluate the clinical and radiological
results of double level osteotomy (distal femoral lateral closed wedge and proximal tibial …

The use of tranexamic acid reduces blood loss in osteotomy at knee level: a systematic review

S Bierke, M Häner, M Bentzin, HU Park… - Knee Surgery, Sports …, 2022 - Springer
Purpose Aim of this systematic review was to evaluate the literature regarding the effect of
tranexamic acid (TXA) on the outcome after knee osteotomy. Methods A systematic literature …

The efficacy and safety of tranexamic acid in foot and ankle surgery: a systematic review and meta-analysis of comparative clinical studies

SP Mirghaderi, MM Aliasin, M Salimi… - Foot and Ankle Surgery, 2023 - Elsevier
Background A comprehensive review of the current evidence investigating the potential
therapeutic effects of tranexamic acid (TXA) and its safety in foot and ankle surgery is …

Effect of Tranexamic Acid on Blood Management during a High Tibial Osteotomy: A Systematic Review and Meta‐analysis

Q Fang, Z Zhang, D Wang, L Wang, W Xiong… - Orthopaedic …, 2022 - Wiley Online Library
This study aimed to evaluate the efficiency and safety of tranexamic acid for blood
management during high tibial osteotomy (HTO). A systematic search was conducted in …

[HTML][HTML] Avoiding compartment syndrome, vascular injury, and neurologic deficit in tibial osteotomy: an observational study of 108 limbs

JS Hoellwarth, A Geffner, AT Fragomen… - … Global Research & …, 2023 - journals.lww.com
Methods: One hundred eight tibia osteotomies performed during 2019 to 2021 were
evaluated, representing all tibia osteotomies except situations of existing infection. A …