Background Prostate-specific antigen (PSA) is a commonly used test to detect prostate
cancer. Attention has mostly focused on the use of PSA in screening asymptomatic patients …

Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …

Background Analysis of circulating tumour DNA could stratify cancer risk in symptomatic
patients. We aimed to evaluate the performance of a methylation-based multicancer early …

The role of conventional serum tumor marker carbohydrate antigen 72-4 (CA72-4) in
assisting diagnosis, monitoring dynamic progression, and evaluating the prognosis of …

Aggressive and recurrent gynecological cancers are associated with worse prognosis and a
lack of effective therapeutic response. Ovarian cancer (OC) patients are often diagnosed in …

Early detection of ovarian cancer remains an important unmet medical need. Effective
screening could reduce mortality by 10%–30%. Used individually, neither serum CA125 nor …

Objectives Non-selective histone deacetylase (HDAC) inhibitors (HDACi) have
demonstrated anti-inflammatory properties in both in vitro and in vivo models of rheumatoid …

Abstract Carbohydrate antigen 125 (CA125) is used for the prediction of the risk of ovarian
malignancy algorithm value as an early diagnosis algorithm of ovarian cancer (OC). Hence …

The grand challenges of ovarian cancer early diagnosis have led to an alarmingly high
mortality rate from ovarian cancer (OC) in the past half century. In vitro diagnosis (IVD) has …

Lung cancer is the second most commonly diagnosed cancer in the world. In terms of the
diagnosis of lung cancer, combination carcinoembryonic antigen (CEA) and cancer antigen …