MRI‐based radiomics and deep learning in biological characteristics and prognosis of hepatocellular carcinoma: Opportunities and challenges

T Xia, B Zhao, B Li, Y Lei, Y Song… - Journal of Magnetic …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fifth most common malignancy and the third leading
cause of cancer‐related death worldwide. HCC exhibits strong inter‐tumor heterogeneity …

[HTML][HTML] Biomarkers and prognostic factors of PD-1/PD-L1 inhibitor-based therapy in patients with advanced hepatocellular carcinoma

N Zhang, X Yang, M Piao, Z Xun, Y Wang, C Ning… - Biomarker …, 2024 - Springer
Systemic therapies using programmed death-1 (PD-1) and programmed death ligand 1 (PD-
L1) inhibitors have demonstrated commendable efficacy in some patients with advanced …

[HTML][HTML] Real-world efficacy and safety of TACE plus camrelizumab and apatinib in patients with HCC (CHANCE2211): a propensity score matching study

ZC Jin, BY Zhong, JJ Chen, HD Zhu, JH Sun… - European …, 2023 - Springer
Objectives This study aimed to investigate the efficacy and safety of transarterial
chemoembolization (TACE) plus camrelizumab, a monoclonal antibody targeting …

[HTML][HTML] Transcatheter arterial chemoembolisation combined with lenvatinib plus camrelizumab as conversion therapy for unresectable hepatocellular carcinoma: a …

XK Wu, LF Yang, YF Chen, ZW Chen, H Lu… - …, 2024 - thelancet.com
Background The synergistic effect of locoregional therapy in combination with systemic
therapy as a conversion therapy for unresectable hepatocellular carcinoma (uHCC) is …

Perioperative safety, oncologic outcome, and risk factors of salvage liver resection for initially unresectable hepatocellular carcinoma converted by transarterial …

KY Lin, ZW Lin, QJ Chen, LP Luo, JX Zhang… - Hepatology …, 2023 - Springer
Background To assess the perioperative safety, oncological outcomes, and determinants
influencing the oncological outcomes of salvage liver resection for initially unresectable …

Hepatic arterial infusion chemotherapy plus lenvatinib and tislelizumab with or without transhepatic arterial embolization for unresectable hepatocellular carcinoma …

S Chen, F Shi, Z Wu, L Wang, H Cai, P Ma… - Journal of …, 2023 - Taylor & Francis
Purpose The current therapeutic strategies for high-risk, unresectable hepatocellular
carcinoma (HCC) patients demonstrate suboptimal outcomes. This study aimed to assess …

Development and experimental validation of a machine learning-based disulfidptosis-related ferroptosis score for hepatocellular carcinoma

C Zhang, T Xu, K Ji, S Cao, J Ai, J Pan, Y Cao, Y Yang… - Apoptosis, 2024 - Springer
Disulfidoptosis and ferroptosis are two distinct programmed cell death pathways that have
garnered considerable attention due to their potential as therapeutic targets. However …

[HTML][HTML] HBV reactivation and its effect on survival in HBV-related hepatocarcinoma patients undergoing transarterial chemoembolization combined with tyrosine …

J Shen, X Wang, N Wang, S Wen, G Yang… - Frontiers in Cellular …, 2023 - frontiersin.org
Objective This study aimed to access hepatitis B virus (HBV) reactivation and its effect on
survival in HBV-related hepatocarcinoma (HCC) patients who underwent transarterial …

Hypoxia-activated cascade nanovaccine for synergistic chemoembolization-immune therapy of hepatocellular carcinoma

Q Shi, W Zhang, Y Zhou, S Huang, J Yu, M Yang… - Biomaterials, 2024 - Elsevier
In this work, a promising treatment strategy for triggering robust antitumor immune
responses in transarterial chemoembolization of hepatocellular carcinoma (HCC) is …

Efficacy and safety of TACE combined with lenvatinib and PD-(L) 1 inhibitor in the treatment of unresectable hepatocellular carcinoma: A retrospective study

H Yang, T Yang, G Qiu, J Liu - Journal of Hepatocellular Carcinoma, 2023 - Taylor & Francis
Purpose In the study, patients with unresectable hepatocellular carcinoma (uHCC) were
treated with either transcatheter chemoembolization (TACE) combined with lenvatinib and …