The human gut is inhabited by a multitude of bacteria, yeasts, and viruses. A dynamic
balance among these microorganisms is associated with the well-being of the human being …

Tuft cells have recently emerged as the focus of intense interest following the discovery of
their chemosensory role in the intestinal tract, and their ability to activate Type 2 immune …

Background Perioperative neurocognitive disorders (PND) are the most common
postoperative complications with few therapeutic options. Gut microbial dysbiosis is …

Developmental exposure to the persistent environmental pollutant, polybrominated diphenyl
ethers (PBDEs), is associated with increased diabetes prevalence. The microbial tryptophan …

An intricate relationship between gut microbiota, diet, and the human body has recently
been extensively investigated. Gut microbiota and gut-derived metabolites, especially …

Intestinal tuft cells (TCs) are defined as chemosensory cells that can “taste” danger and
induce immune responses. They play a critical role in gastrointestinal parasite invasion …

While weight gain is associated with a host of chronic illnesses, efforts in obesity have relied
on single" snapshots" of body mass index (BMI) to guide genetic and molecular discovery …

Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in
reproductive-aged women. The occurrence of PCOS was reported to be associated with the …

Tuft cells are more than guardian chemosensory elements of the digestive tract. They
produce a variety of immunological effector molecules in response to stimulation; moreover …

Tuft cells, also known as taste chemosensory cells, accumulate during parasite colonization
or infection and have powerful immunomodulatory effects on substances that could be …