The wing imaginal disc

BK Tripathi, KD Irvine - Genetics, 2022 - academic.oup.com
The Drosophila wing imaginal disc is a tissue of undifferentiated cells that are precursors of
the wing and most of the notum of the adult fly. The wing disc first forms during …

The sponge microbiome project

L Moitinho-Silva, S Nielsen, A Amir, A Gonzalez… - …, 2017 - academic.oup.com
Rhododendron delavayi Franch. is globally famous as an ornamental plant. Its distribution in
southwest China covers several different habitats and environments. However, not much …

Cancer drug development using drosophila as an in vivo tool: from bedside to bench and back

AK Yadav, S Srikrishna, SC Gupta - Trends in Pharmacological Sciences, 2016 - cell.com
The fruit fly Drosophila melanogaster has been used for modeling cancer and as an in vivo
tool for the validation and/or development of cancer therapeutics. The impetus for the use of …

[HTML][HTML] Specification and Patterning of Drosophila Appendages

M Ruiz-Losada, D Blom-Dahl, S Córdoba… - Journal of developmental …, 2018 - mdpi.com
Appendages are external projections of the body that serve the animal for locomotion,
feeding, or environment exploration. The appendages of the fruit fly Drosophila …

Decapentaplegic and growth control in the developing Drosophila wing

T Akiyama, MC Gibson - Nature, 2015 - nature.com
As a central model for morphogen action during animal development, the bone
morphogenetic protein 2/4 (BMP2/4)-like ligand Decapentaplegic (Dpp) is proposed to form …

A Multivariate Genome-Wide Association Study of Wing Shape in Drosophila melanogaster

W Pitchers, J Nye, EJ Márquez, A Kowalski, I Dworkin… - Genetics, 2019 - academic.oup.com
Due to the complexity of genotype–phenotype relationships, simultaneous analyses of
genomic associations with multiple traits will be more powerful and informative than a series …

[HTML][HTML] Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

S Matsuda, JV Schaefer, Y Mii, Y Hori, D Bieli… - Nature …, 2021 - nature.com
How morphogen gradients control patterning and growth in developing tissues remains
largely unknown due to lack of tools manipulating morphogen gradients. Here, we generate …

[HTML][HTML] Epithelial organ shape is generated by patterned actomyosin contractility and maintained by the extracellular matrix

A Nematbakhsh, M Levis, N Kumar… - PLoS computational …, 2020 - journals.plos.org
Epithelial sheets define organ architecture during development. Here, we employed an
iterative multiscale computational modeling and quantitative experimental approach to …

Sizing it up: the mechanical feedback hypothesis of organ growth regulation

A Buchmann, M Alber, JJ Zartman - Seminars in cell & developmental …, 2014 - Elsevier
The question of how the physical dimensions of animal organs are specified has long
fascinated both experimentalists and computational scientists working in the field of …

Positive and relaxed selection associated with flight evolution and loss in insect transcriptomes

TF Mitterboeck, S Liu, SJ Adamowicz, J Fu… - …, 2017 - academic.oup.com
The evolution of powered flight is a major innovation that has facilitated the success of
insects. Previously, studies of birds, bats, and insects have detected molecular signatures of …