Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.
N Kato, M Hijikata, Y Ootsuyama… - Proceedings of the …, 1990 - National Acad Sciences
The nucleotide sequence of the Japanese type of hepatitis C virus (HCV-J) genome,
consisting of 9413 nucleotides, was determined by analyses of cDNA clones from plasma …
consisting of 9413 nucleotides, was determined by analyses of cDNA clones from plasma …
Hepatocellular carcinoma: a worldwide problem and the major risk factors
RG Simonetti, C Cammà, F Fiorello, F Politi… - Digestive diseases and …, 1991 - Springer
Male sex, age, cirrhosis, and HB s Ag are the major risk factors for hepatocellular carcinoma
(HCC). The geographic distribution of HCC is highly uneven, such that three distinct …
(HCC). The geographic distribution of HCC is highly uneven, such that three distinct …
Prospective analysis of risk factors for hepatocellular carcinoma in patients with liver cirrhosis
RF Velázquez, M Rodrı́guez, CA Navascués, A Linares… - Hepatology, 2003 - Elsevier
Better knowledge of the risk factors associated with the appearance of hepatocellular
carcinoma (HCC) could improve the efficacy of surveillance programs. A total of 463 patients …
carcinoma (HCC) could improve the efficacy of surveillance programs. A total of 463 patients …
Hepatocellular carcinoma: epidemiology, risk factors, and screening
M Sherman - Seminars in liver disease, 2005 - thieme-connect.com
In this article, the epidemiology of hepatocellular carcinoma (HCC), risk factors for the
development of HCC, and how these factors affect the decision about whether an individual …
development of HCC, and how these factors affect the decision about whether an individual …
Randomised trial of effects of interferon-α on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis
S Nishiguchi, T Kuroki, S Nakatani, H Morimoto… - The Lancet, 1995 - thelancet.com
Patients with chronic active hepatitis C and cirrhosis often develop hepatocellular
carcinoma. Interferon (IFN) seems to be effective in some patients but whether it prevents …
carcinoma. Interferon (IFN) seems to be effective in some patients but whether it prevents …
[PDF][PDF] Screening for hepatocellular carcinoma
J Collier, M Sherman - Hepatology, 1998 - Wiley Online Library
In contrast to certain other cancers, 1-4 screening for liver cancer has become, at least
among hepatologists, an accepted part of the management of patients with end-stage liver …
among hepatologists, an accepted part of the management of patients with end-stage liver …
A multivariate analysis of risk factors for hepatocellular carcinogenesis: a prospective observation of 795 patients with viral and alcoholic cirrhosis
K Ikeda, S Saitoh, I Koida, Y Arase, A Tsubota… - Hepatology, 1993 - journals.lww.com
To elucidate the appearance rates of hepatocellular carcinoma in cirrhosis and to assess the
risk factors for hepatocellular carcinogenesis, we prospectively studied 795 consecutive …
risk factors for hepatocellular carcinogenesis, we prospectively studied 795 consecutive …
Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites
A Grakoui, DW McCourt, C Wychowski… - Journal of …, 1993 - Am Soc Microbiol
Processing of the hepatitis C virus (HCV) H strain polyprotein yields at least nine distinct
cleavage products: NH2-C-E1-E2-NS2-NS3-NS4A-NS4B-NS5A-NS5B-CO OH. As …
cleavage products: NH2-C-E1-E2-NS2-NS3-NS4A-NS4B-NS5A-NS5B-CO OH. As …
[HTML][HTML] Staging systems in hepatocellular carcinoma
F Pons, M Varela, JM Llovet - Hpb, 2005 - Elsevier
Staging systems are key to predict the prognosis of patients with cancer, to stratify the
patients according to prognostic variables in the setting of clinical trials, to allow the …
patients according to prognostic variables in the setting of clinical trials, to allow the …
Epidemiological characteristics and risk factors of hepatocellular carcinoma
CJEN CHEN, MW YU… - … of gastroenterology and …, 1997 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking
variation in HCC incidence rates between various countries, with a highest‐to‐lowest ratio of …
variation in HCC incidence rates between various countries, with a highest‐to‐lowest ratio of …