Peripheral muscle dysfunction is an important systemic consequence of cystic fibrosis (CF)
with major clinical implications, such as exercise intolerance and reduced quality of life …

Exercise intolerance is common in people with CF (pwCF), but not universal among all
individuals. While associated with disease prognosis, exercise intolerance is not simply a …

There are limited reports that compare muscle strength, functional exercise capacity,
activities of daily living (ADL) and parameters of physical fitness of cystic fibrosis (CF) …

G551D, a mutation of the cystic fibrosis transmembrane conductance regulator (CFTR)
gene, results in impaired chloride channel function in cystic fibrosis (CF) with multiple end …

Background Previous research has found conflictive results regarding the benefits of
inspiratory muscle training (IMT) for cystic fibrosis (CF) patients. Also, involvement of …

Rationale: Cystic fibrosis transmembrane conductance regulator (CFTR) is expressed in
human skeletal muscle cells. Variations of CFTR dysfunction among patients with cystic …

Cystic fibrosis (CF) is a genetic, multisystemic disorder with broad clinical manifestations
apart from the well-characterized pulmonary dysfunction. Recent findings have described …

Cystic fibrosis (CF), a severe life-limiting disease, is associated with multi-organ pathologies
that contribute to a reduced exercise capacity. At present, the impact of, and interaction …

Background Several tests may be used to assess exercise intolerance in cystic fibrosis (CF),
including the gold standard cardiopulmonary exercise test (CPET) and the Modified Shuttle …

Objectives The long-term cardiopulmonary outcomes following preterm birth during the
surfactant era remain unclear. Respiratory symptoms, particularly exertional symptoms, are …