Long QT syndrome (LQTS) is an inherited primary arrhythmia syndrome that may present
with malignant arrhythmia and, rarely, risk of sudden death. The clinical symptoms include …

Background Alzheimer's disease (AD) is an insidious, irreversible, and progressive
neurodegenerative health condition manifesting as cognitive deficits and amyloid beta (Aβ) …

The benefits of the complex microscopic and industrially important group of microalgae such
as diatoms is not hidden and have lately surprised the scientific community with their …

RNA-guided genomic transcriptional regulation tools, namely clustered regularly
interspaced short palindromic repeats interference (CRISPRi) and CRISPR-mediated gene …

Cancer is a severe disease that substantially jeopardizes global health. Although
considerable efforts have been made to discover effective anti-cancer therapeutics, the …

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated
protein (Cas) system has revolutionized the ability to edit the mammalian genome, providing …

Photosynthetic microorganisms like microalgae and cyanobacteria are quickly gaining
recognition for their financial potential and have recently been subjected to research into …

Targeted genome editing using RNA-guided endonucleases is an emerging tool in algal
biotechnology. Recently, CRISPR–Cas systems have been widely used to manipulate the …

Non-homologous end joining (NHEJ), and to a lesser extent, the error-free pathway known
as homology-directed repair (HDR) are cellular mechanisms for recovery from double-strand …

The evolution of organisms has provided a variety of mechanisms to maintain the integrity of
its genome, but as damage occurs, DNA damage repair pathways are necessary to resolve …