This statement summarizes evidence that adverse pregnancy outcomes (APOs) such as
hypertensive disorders of pregnancy, preterm delivery, gestational diabetes, small-for …

Pre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical
presentation is highly variable but hypertension and proteinuria are usually seen. These …

Importance Preeclampsia is one of the most serious health problems that affect pregnant
persons. It is a complication in approximately 4% of pregnancies in the US and contributes …

Preeclampsia (PE) is a multisystem disorder that typically affects 2%− 5% of pregnant
women and is one of the leading causes of maternal and perinatal morbidity and mortality …

Importance Potentially harmful mutations of the breast cancer susceptibility 1 and 2 genes
(BRCA1/2) are associated with increased risk for breast, ovarian, fallopian tube, and …

Preeclampsia is defined as new-onset hypertension after the 20th wk of gestation along with
evidence of maternal organ failure. Rates of preeclampsia have steadily increased over the …

Importance Ovarian cancer is relatively rare but the fifth-leading cause of cancer mortality
among United States women. Objective To systematically review evidence on benefits and …

Hypertension accounts for 1 in 5 deaths among American women, posing a greater burden
for women than men, and is among their most important risk factors for death and …

Context Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of
reproductive-aged women, affecting approximately 5% to 20% of women of reproductive …

Abstract Purpose of Review Hypertensive disorders of pregnancy (HDP)—gestational
hypertension, preeclampsia, and eclampsia—are a leading cause of adverse maternal and …